B3E1J2 · B3E1J2_TRIL1

Function

function

May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site55substrate
Binding site130substrate
Binding site190substrate
Binding site191-193NAD+ (UniProtKB | ChEBI)
Binding site220substrate
Binding site224substrate
Binding site225NAD+ (UniProtKB | ChEBI)
Binding site254-259NAD+ (UniProtKB | ChEBI)
Binding site256-261NAD+ (UniProtKB | ChEBI)
Binding site277NAD+ (UniProtKB | ChEBI)
Binding site312NAD+ (UniProtKB | ChEBI)
Binding site333-335NAD+ (UniProtKB | ChEBI)
Binding site378NAD+ (UniProtKB | ChEBI)
Binding site385NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylhomocysteinase activity
Biological ProcessL-homocysteine biosynthetic process
Biological Processone-carbon metabolic process
Biological ProcessS-adenosylmethionine cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylhomocysteinase
  • EC number
  • Alternative names
    • S-adenosyl-L-homocysteine hydrolase
      (AdoHcyase
      )

Gene names

    • Name
      ahcY
    • Ordered locus names
      Glov_0356

Organism names

Accessions

  • Primary accession
    B3E1J2

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain225-384S-adenosyl-L-homocysteine hydrolase NAD binding

Sequence similarities

Belongs to the adenosylhomocysteinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    464
  • Mass (Da)
    50,826
  • Last updated
    2008-07-22 v1
  • Checksum
    06B959E9AC10E1B3
MGTDYIVADLGLADWGRKEIKIAETEMPGLMAIREEYAASQPLKGARITGSLHMTIQTAVLIETLTALGAQVRWASCNIFSTQDHAAAAIAASGVPVFAVKGESLTDYWDYTHKIFEWADGGFSNMILDDGGDATLLLHLGSKAEKDLSVLNNPGSEEETILFAAIKAKLAVDPTWYSVRLAQIKGVTEETTTGVHRLYQMHERGELAFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMVAGKVALVCGYGDVGKGSAQALRALSAQVWVTEIDPICALQAAMEGYRVVTMEYAADKADIFVTCTGNYHVITHEHLLKMKDQAIVCNIGHFDNEIEVAALEQYQWEEIKPQVDHIILPSGNRIILLAKGRLVNLGCATGHPSYVMSSSFANQTIAQIEIFCNPGKYPTGVYVLPKHLDEKVARLQLKKLNAQLSVLTKEQADYIGVPVEGPYKAEHYRY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001089
EMBL· GenBank· DDBJ
ACD94084.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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