B3DZZ7 · GPMA_METI4
- Protein2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
- GenegpmA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids248 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
Catalytic activity
- (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate
Pathway
Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 7-14 | substrate | ||||
Sequence: RHGESIWN | ||||||
Active site | 8 | Tele-phosphohistidine intermediate | ||||
Sequence: H | ||||||
Binding site | 20-21 | substrate | ||||
Sequence: TG | ||||||
Binding site | 59 | substrate | ||||
Sequence: R | ||||||
Active site | 86 | Proton donor/acceptor | ||||
Sequence: E | ||||||
Binding site | 86-89 | substrate | ||||
Sequence: ERHY | ||||||
Binding site | 97 | substrate | ||||
Sequence: K | ||||||
Binding site | 113-114 | substrate | ||||
Sequence: RR | ||||||
Site | 181 | Transition state stabilizer | ||||
Sequence: H | ||||||
Binding site | 182-183 | substrate | ||||
Sequence: GN |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity | |
Biological Process | gluconeogenesis | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
- EC number
- Short namesBPG-dependent PGAM ; PGAM ; Phosphoglyceromutase ; dPGM
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Verrucomicrobiota > Methylacidiphilae > Methylacidiphilales > Methylacidiphilaceae > Methylacidiphilum (ex Ratnadevi et al. 2023)
Accessions
- Primary accessionB3DZZ7
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000135958 | 1-248 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | |||
Sequence: MKVVFLRHGESIWNRENRFTGWTDVDLSSRGIEEAENAARLLKEEGFEFDVAFCSVLKRAIRTLWIVLDKMDRMWIPVEKSWRLNERHYGALQGLNKSEMAKKYGEEQVLLWRRSYDIVPPRLENDDPRHPRFDPRYRSLPADELPAAESLKDTLERTVPYWKERIFPAILSGQKVLVSAHGNSIRALIKYIENMSEKEIVGLNIPTGFPLVYDLDEQGNKLACYYLGDLEEIEKAQHRVAAQGKASS |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length248
- Mass (Da)28,765
- Last updated2008-07-22 v1
- ChecksumA9345B9053D6E3DC
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000975 EMBL· GenBank· DDBJ | ACD82658.1 EMBL· GenBank· DDBJ | Genomic DNA |