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B3DYY7 · B3DYY7_METI4

Function

function

Resistance to Hg2+ in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg0.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per subunit.

Features

Showing features for binding site.

155050100150200250300350400450500550
TypeIDPosition(s)Description
Binding site133FAD (UniProtKB | ChEBI)
Binding site222-224FAD (UniProtKB | ChEBI)
Binding site259-266NAD+ (UniProtKB | ChEBI)
Binding site282NAD+ (UniProtKB | ChEBI)
Binding site350NAD+ (UniProtKB | ChEBI)
Binding site391FAD (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionmercury (II) reductase (NADP+) activity
Molecular Functionmercury ion binding
Molecular FunctionNADP binding
Molecular Functionoxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
Biological Processdetoxification of mercury ion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mercuric reductase
  • EC number
  • Alternative names
    • Hg(II) reductase

Gene names

    • Name
      merA
    • Ordered locus names
      Minf_0451

Organism names

Accessions

  • Primary accession
    B3DYY7

Proteomes

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond124↔129Redox-active

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-69HMA

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    550
  • Mass (Da)
    59,222
  • Last updated
    2008-07-22 v1
  • MD5 Checksum
    CAF5B11C4A613CF0EFBFF94A6F7B8907
MSKRIIVQIEGMHCADCARRLKEALGNIEGVEEVDIPDWRTKKGTLVIDENLNIDDILKGIERSGYRGTVTGQEPFESIKEREKKDYDLLIIGGGSAAFAAAIKAAELGANIGIVEESTIGGTCVNVGCIPSKFLIRAAEIYHWASHPRFAGLKAAPLSLNWKELVDQKEKLVNSLRQSKYIHLLDVYPQISLIRGKARLAQGNRVIVGDKSYSSRKILIATGSSPSIPPVPGLKETGCLDSTTALDLKTLPASLAVIGAGAIGLELGQMFSRFGVKVVLLEALPAIAMAEEPEIRDSLHRYLEEEGIEIFTHTQILQVEKKGSKHKRLSVQKEGKVIEMEVEQILAATGRVANTNGLGLEEVGVKVTNRGAILVDEFLRTTNPEIYAAGDCASLPQFVYVSAYTGGVAAENAISGKNRAIDLSSLPRVTFTDPQIASVGLTEDQAKEAGYSTIVALLPIQEVPKAIVSLDSRGLVKLVAEEKTGRLIGAHVLAAAAGDVIEEAVLALRHGLTYQDIIEALHPYLTMAEAFKLAALTFKKDVGRLSCCAT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000975
EMBL· GenBank· DDBJ
ACD82509.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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