B3DXI5 · B3DXI5_METI4
- ProteinThreonylcarbamoyl-AMP synthase
- Genesua5
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids324 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine.
Catalytic activity
- L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 33 | L-threonine (UniProtKB | ChEBI) | |||
Binding site | 56 | ATP (UniProtKB | ChEBI) | |||
Binding site | 65 | L-threonine (UniProtKB | ChEBI) | |||
Binding site | 119 | L-threonine (UniProtKB | ChEBI) | |||
Binding site | 139 | L-threonine (UniProtKB | ChEBI) | |||
Binding site | 141 | ATP (UniProtKB | ChEBI) | |||
Binding site | 149 | ATP (UniProtKB | ChEBI) | |||
Binding site | 179 | L-threonine (UniProtKB | ChEBI) | |||
Binding site | 193 | ATP (UniProtKB | ChEBI) | |||
Binding site | 229 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | double-stranded RNA binding | |
Molecular Function | L-threonylcarbamoyladenylate synthase | |
Molecular Function | tRNA binding | |
Biological Process | regulation of translational fidelity | |
Biological Process | tRNA processing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThreonylcarbamoyl-AMP synthase
- EC number
- Short namesTC-AMP synthase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Verrucomicrobiota > Methylacidiphilae > Methylacidiphilales > Methylacidiphilaceae > Methylacidiphilum (ex Ratnadevi et al. 2023)
Accessions
- Primary accessionB3DXI5
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length324
- Mass (Da)35,672
- Last updated2008-07-22 v1
- Checksum5803F98FC594E4D8
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000975 EMBL· GenBank· DDBJ | ACD82219.1 EMBL· GenBank· DDBJ | Genomic DNA |