B2XLB2 · B2XLB2_HUMAN

  • Protein
    NADH-ubiquinone oxidoreductase chain 3
  • Gene
    ND3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 3
  • EC number

Gene names

    • Name
      ND3

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • L501
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    B2XLB2

Subcellular Location

Membrane
Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-24Helical
Transmembrane55-78Helical
Transmembrane84-107Helical

Keywords

PTM/Processing

Proteomic databases

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. Interacts with TMEM186. Interacts with TMEM242.

Family & Domains

Sequence similarities

Belongs to the complex I subunit 3 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    115
  • Mass (Da)
    13,162
  • Last updated
    2008-07-01 v1
  • Checksum
    EBD62CFCAAF16007
MNFALILMINTLLALLLMTITFWMPQLNGYMEKSTPYECGFDPMSPARVPFSMKFFLVAITFLLFDLEIALLLPLPWALQTTNLPLMVMSSLLLIIILALSLAYEWLQKGLDWAE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU092842
EMBL· GenBank· DDBJ
ABU66369.1
EMBL· GenBank· DDBJ
Genomic DNA
KC345930
EMBL· GenBank· DDBJ
AGD84052.1
EMBL· GenBank· DDBJ
Genomic DNA
KC345931
EMBL· GenBank· DDBJ
AGD84065.1
EMBL· GenBank· DDBJ
Genomic DNA
KC346148
EMBL· GenBank· DDBJ
AGD86886.1
EMBL· GenBank· DDBJ
Genomic DNA
KC346224
EMBL· GenBank· DDBJ
AGD87874.1
EMBL· GenBank· DDBJ
Genomic DNA
KC346229
EMBL· GenBank· DDBJ
AGD87939.1
EMBL· GenBank· DDBJ
Genomic DNA
KC533475
EMBL· GenBank· DDBJ
AGK64420.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248280
EMBL· GenBank· DDBJ
QFV14428.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248281
EMBL· GenBank· DDBJ
QFV14441.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248285
EMBL· GenBank· DDBJ
QFV14493.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248286
EMBL· GenBank· DDBJ
QFV14506.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248290
EMBL· GenBank· DDBJ
QFV14558.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248294
EMBL· GenBank· DDBJ
QFV14610.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248298
EMBL· GenBank· DDBJ
QFV14662.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248315
EMBL· GenBank· DDBJ
QFV14883.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248316
EMBL· GenBank· DDBJ
QFV14896.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248331
EMBL· GenBank· DDBJ
QFV15091.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248335
EMBL· GenBank· DDBJ
QFV15143.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248341
EMBL· GenBank· DDBJ
QFV15221.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248342
EMBL· GenBank· DDBJ
QFV15234.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248343
EMBL· GenBank· DDBJ
QFV15247.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248345
EMBL· GenBank· DDBJ
QFV15273.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248346
EMBL· GenBank· DDBJ
QFV15286.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248347
EMBL· GenBank· DDBJ
QFV15299.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248348
EMBL· GenBank· DDBJ
QFV15312.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248352
EMBL· GenBank· DDBJ
QFV15364.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248353
EMBL· GenBank· DDBJ
QFV15377.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248354
EMBL· GenBank· DDBJ
QFV15390.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248356
EMBL· GenBank· DDBJ
QFV15416.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248357
EMBL· GenBank· DDBJ
QFV15429.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248361
EMBL· GenBank· DDBJ
QFV15481.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248363
EMBL· GenBank· DDBJ
QFV15507.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248380
EMBL· GenBank· DDBJ
QFV15728.1
EMBL· GenBank· DDBJ
Genomic DNA
MK248447
EMBL· GenBank· DDBJ
QFV16599.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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