B2XBQ5 · 85A19_PRUDU

Function

function

Involved in the biosynthesis of the cyanogenic glycoside (R)-prunasin, a precursor of (R)-amygdalin, which at high concentrations is associated with intense bitterness in kernels of almond (PubMed:32688778).
Stereo-selectively glucosylates (R)-mandelonitrile to produce (R)-prunasin (PubMed:32688778).

Catalytic activity

Features

Showing features for active site, binding site.

148350100150200250300350400450
TypeIDPosition(s)Description
Active site22Proton acceptor
Binding site22an anthocyanidin (UniProtKB | ChEBI)
Active site124Charge relay
Binding site146UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site363UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site378UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site381UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site382UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site383UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site386UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site401an anthocyanidin (UniProtKB | ChEBI)
Binding site402UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site403UDP-alpha-D-glucose (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionUDP-glycosyltransferase activity

Keywords

Enzyme and pathway databases

Protein family/group databases

    • GT1Glycosyltransferase Family 1

Names & Taxonomy

Protein names

  • Recommended name
    (R)-mandelonitrile beta-glucosyltransferase
  • EC number
  • Alternative names
    • UDP-glycosyltransferase 85A19

Gene names

    • Name
      UGT85A19
    • ORF names
      ALMOND_2B036004

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Texas
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Rosales > Rosaceae > Amygdaloideae > Amygdaleae > Prunus

Accessions

  • Primary accession
    B2XBQ5
  • Secondary accessions
    • A0A5E4FTL8

Proteomes

Genome annotation databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004514841-483(R)-mandelonitrile beta-glucosyltransferase

Structure

Family & Domains

Sequence similarities

Belongs to the UDP-glycosyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    483
  • Mass (Da)
    53,697
  • Last updated
    2020-12-02 v2
  • Checksum
    2B6252C85CB4F203
MSPVASKEKPHAVFVPFPAQGHINPMLQLAKLLNYKGFHITFVNTEFNHKRMLESQGSHALDGLPSFRFETIPDGLPPADADARRNLPLVCDSTSKTCLAPFEALLTKLNSSPDSPPVTCIVADGVTSFTLDAAEHFGIPEVLFWTTSACGLMGYVQYYRLIEKGLTPFKDAKDFANGYLDTEIDWIPGMKDVRLKDMPSFIRTTDPNDIMLHYMVSETERSKKASAIILNTFDALEQEVVDALSTLLPPIYSIGPLQLPYSEIPSEYNDLKAIGSNLWAENTECLNWLDTKEPNSVVYVNFGSTTVMTNEQLVEFSWGLANSKKPFLWIIRPGLVAGETAVVPPEFLEETKERGMLASWCPQEQVLLHSAIGGFLTHSGWNSTLEALCGGVPLICWPFFAEQQTNVRYSCTQWGIGIEIDGEVKRDYIDGLVRTLMDGEEGKKMRKKALEWKMLAEDATAPKGSSYLALENVVSKVLLSPRD

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict127in Ref. 1; ABV68925
Sequence conflict454in Ref. 1; ABV68925
Sequence conflict461in Ref. 1; ABV68925

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU015987
EMBL· GenBank· DDBJ
ABV68925.1
EMBL· GenBank· DDBJ
mRNA
CABIKO010000198
EMBL· GenBank· DDBJ
VVA30855.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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