B2WCB2 · MTNB_PYRTR
- ProteinMethylthioribulose-1-phosphate dehydratase
- Genemde1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids232 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
Catalytic activity
- 5-(methylsulfanyl)ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | methylthioribulose 1-phosphate dehydratase activity | |
Molecular Function | zinc ion binding | |
Biological Process | L-methionine salvage from methylthioadenosine | |
Biological Process | L-methionine salvage from S-adenosylmethionine |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethylthioribulose-1-phosphate dehydratase
- EC number
- Short namesMTRu-1-P dehydratase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Pleosporomycetidae > Pleosporales > Pleosporineae > Pleosporaceae > Pyrenophora
Accessions
- Primary accessionB2WCB2
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000393844 | 1-232 | Methylthioribulose-1-phosphate dehydratase | |||
Sequence: MASNDIDAEALVHSDDPSHPANHICTLCAKFYNLGWVTGTGGGTSIRHEDKIYIAPSGVQKELMKPTDMFVMDFNSKEYLRKPQVLKPSACTPLFLAAFERGAGCCIHTHSQWAVLVTLIVERDFGKDACFEIEEIEQIKGIPKGRGKQGNLGYYDRLRIPIIENTAHEEDLRESLEEAMEKYPDSYAILVKRHGIYVWGDNVHKAKTQCESIDYILQLAVEMKKLGLPWTK |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length232
- Mass (Da)26,171
- Last updated2008-07-01 v1
- Checksum03C7A6F2E9DCE348
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DS231622 EMBL· GenBank· DDBJ | EDU50540.1 EMBL· GenBank· DDBJ | Genomic DNA |