B2WCB2 · MTNB_PYRTR

Function

function

Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site91substrate
Binding site108Zn2+ (UniProtKB | ChEBI)
Binding site110Zn2+ (UniProtKB | ChEBI)
Active site137Proton donor/acceptor
Binding site194Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmethylthioribulose 1-phosphate dehydratase activity
Molecular Functionzinc ion binding
Biological ProcessL-methionine salvage from methylthioadenosine
Biological ProcessL-methionine salvage from S-adenosylmethionine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylthioribulose-1-phosphate dehydratase
  • EC number
  • Short names
    MTRu-1-P dehydratase

Gene names

    • Name
      mde1
    • ORF names
      PTRG_07621

Organism names

Accessions

  • Primary accession
    B2WCB2

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003938441-232Methylthioribulose-1-phosphate dehydratase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the aldolase class II family. MtnB subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    232
  • Mass (Da)
    26,171
  • Last updated
    2008-07-01 v1
  • Checksum
    03C7A6F2E9DCE348
MASNDIDAEALVHSDDPSHPANHICTLCAKFYNLGWVTGTGGGTSIRHEDKIYIAPSGVQKELMKPTDMFVMDFNSKEYLRKPQVLKPSACTPLFLAAFERGAGCCIHTHSQWAVLVTLIVERDFGKDACFEIEEIEQIKGIPKGRGKQGNLGYYDRLRIPIIENTAHEEDLRESLEEAMEKYPDSYAILVKRHGIYVWGDNVHKAKTQCESIDYILQLAVEMKKLGLPWTK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DS231622
EMBL· GenBank· DDBJ
EDU50540.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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