B2SYC8 · B2SYC8_PARPJ

Function

function

Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO3- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO3- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site113ATP (UniProtKB | ChEBI)
Binding site156ATP (UniProtKB | ChEBI)
Binding site161-167ATP (UniProtKB | ChEBI)
Binding site191-194ATP (UniProtKB | ChEBI)
Binding site199ATP (UniProtKB | ChEBI)
Binding site222ATP (UniProtKB | ChEBI)
Binding site277-278ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function5-(carboxyamino)imidazole ribonucleotide synthase activity
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionphosphoribosylaminoimidazole carboxylase activity
Biological Process'de novo' IMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    N5-carboxyaminoimidazole ribonucleotide synthase
  • EC number
  • Short names
    N5-CAIR synthase
  • Alternative names
    • 5-(carboxyamino)imidazole ribonucleotide synthetase

Gene names

    • Name
      purK
    • Ordered locus names
      Bphyt_3272

Organism names

Accessions

  • Primary accession
    B2SYC8

Proteomes

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain117-307ATP-grasp

Sequence similarities

Belongs to the PurK/PurT family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    398
  • Mass (Da)
    42,292
  • Last updated
    2008-07-01 v1
  • Checksum
    5B620521FB632F00
MNPDNTPVSPILPGAWLGMVGGGQLGRMFCFAAQAMGYRVAVLDPDENSPAGAVADRHLRAAYDDEASLTELARLCAAVSTEFENVPAASLDFLARTTFVSPAGRCVAVAQDRIAEKRFIASSGVAVAPHVVIESSDALAALDDAKLEAVLPGILKTARMGYDGKGQIRVRNAEEVREAHASLAGVPCVLEKRLPLKFEVSALIARAASGASVVYPLAQNTHRDGVLSHTIVPAPDASATLVQQAQQAALQIADKLGYVGVLCVEFFILEDGSLVANEMAPRPHNSGHYTVDACATSQFEQQVRAMTGMPLGDTRQHSPAVMLNILGDVWFPDGPKRAAVTPPWQEVAAMPAARLHLYGKEEARCGRKMGHVNFTAATLEEARTAGRDCARLLHIITS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001052
EMBL· GenBank· DDBJ
ACD17663.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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