B2S4V2 · NDK_BRUA1

Function

function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site11ATP (UniProtKB | ChEBI)
Binding site59ATP (UniProtKB | ChEBI)
Binding site87ATP (UniProtKB | ChEBI)
Binding site93ATP (UniProtKB | ChEBI)
Binding site104ATP (UniProtKB | ChEBI)
Binding site114ATP (UniProtKB | ChEBI)
Active site117Pros-phosphohistidine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionnucleoside diphosphate kinase activity
Biological ProcessCTP biosynthetic process
Biological ProcessGTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoside diphosphate kinase
  • EC number
  • Short names
    NDK
    ; NDP kinase
  • Alternative names
    • Nucleoside-2-P kinase

Gene names

    • Name
      ndk
    • Ordered locus names
      BAbS19_I06680

Organism names

  • Taxonomic identifier
  • Strain
    • S19
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Brucellaceae > Brucella/Ochrobactrum group > Brucella

Accessions

  • Primary accession
    B2S4V2

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001249351-140Nucleoside diphosphate kinase

Keywords

Interaction

Subunit

Homotetramer.

Structure

Family & Domains

Sequence similarities

Belongs to the NDK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    140
  • Mass (Da)
    15,278
  • Last updated
    2008-07-01 v1
  • Checksum
    847A9A8D83E4ACBA
MAIERTFSMIKPDATRRNLTGAIIAKLEEAGLRVVASKRVWMSRREAEGFYAVHKDRPFFGELVEFMSSGPTVVQVLEGENAIAKNREVMGATNPANADEGTIRKTFALSIGENSVHGSDAPETAAEEIAYWFSGTEIVG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000887
EMBL· GenBank· DDBJ
ACD72199.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help