B2RWP4 · B2RWP4_HUMAN
- ProteinTACC2 protein
- GeneTACC2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2826 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | cytoskeleton | |
Biological Process | mitotic spindle organization |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionB2RWP4
Subcellular Location
Disease & Variants
Organism-specific databases
PTM/Processing
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | B2RWP4 | BORCS6 Q96GS4 | 6 | EBI-14211313, EBI-10193358 | |
BINARY | B2RWP4 | CLK2 P49760 | 3 | EBI-14211313, EBI-750020 | |
BINARY | B2RWP4 | CLVS2 Q5SYC1 | 3 | EBI-14211313, EBI-12357161 | |
BINARY | B2RWP4 | GRAMD4 Q6IC98 | 3 | EBI-14211313, EBI-10962409 | |
BINARY | B2RWP4 | TGM1 P22735 | 3 | EBI-14211313, EBI-2562368 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-36 | Polar residues | ||||
Sequence: MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQ | ||||||
Region | 1-304 | Disordered | ||||
Sequence: MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDL | ||||||
Compositional bias | 184-198 | Polar residues | ||||
Sequence: QKSSFSFSSGIDQSP | ||||||
Compositional bias | 242-265 | Polar residues | ||||
Sequence: GVASVQVTPEAPAAAQQGTESSAV | ||||||
Region | 314-333 | Disordered | ||||
Sequence: RSNSGAAPEAEVNAASQESC | ||||||
Region | 392-453 | Disordered | ||||
Sequence: AAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVS | ||||||
Region | 465-785 | Disordered | ||||
Sequence: LVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGE | ||||||
Compositional bias | 510-543 | Pro residues | ||||
Sequence: QPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESA | ||||||
Compositional bias | 602-632 | Basic and acidic residues | ||||
Sequence: FSSKRDPEVGKDELSKPSSDAESRDHPSSHS | ||||||
Region | 825-964 | Disordered | ||||
Sequence: SSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKDQGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQSSRVSPP | ||||||
Compositional bias | 826-843 | Polar residues | ||||
Sequence: SEKHLQPSQAQPETSIFD | ||||||
Compositional bias | 886-935 | Polar residues | ||||
Sequence: NLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSA | ||||||
Compositional bias | 985-1000 | Polar residues | ||||
Sequence: CTGQGPNKSQQALADA | ||||||
Region | 985-1050 | Disordered | ||||
Sequence: CTGQGPNKSQQALADALEEGSQHEEACQRHPGASEAADGCSPLWGLSKREMASGNTGEAPPCQPDS | ||||||
Region | 1062-1155 | Disordered | ||||
Sequence: ALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECRATSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGEATL | ||||||
Region | 1242-1275 | Disordered | ||||
Sequence: SAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPP | ||||||
Region | 1296-1400 | Disordered | ||||
Sequence: QPGAAGGEIPAVQASSGSPKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKAATAPGAGAKASGEGMAGDAAGETEGSMERMGEPSQDPKQGTSGGVDTSSEQIA | ||||||
Compositional bias | 1382-1400 | Polar residues | ||||
Sequence: QDPKQGTSGGVDTSSEQIA | ||||||
Region | 1427-1458 | Disordered | ||||
Sequence: PGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGV | ||||||
Region | 1493-1661 | Disordered | ||||
Sequence: ASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSGKQHQETSACDSPHGEDGPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEANSEPWTLDTLGGERR | ||||||
Compositional bias | 1547-1561 | Polar residues | ||||
Sequence: SQLERSRQELASGLP | ||||||
Region | 1675-1705 | Disordered | ||||
Sequence: LGNQSTPAPPTGEVADTPLEPGKVAGAAGEA | ||||||
Region | 1741-1878 | Disordered | ||||
Sequence: VLPGSCQDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESPT | ||||||
Compositional bias | 1798-1822 | Basic and acidic residues | ||||
Sequence: PEPDETHDPKLQHLAPEELHTDRES | ||||||
Compositional bias | 1837-1851 | Basic and acidic residues | ||||
Sequence: DAPRVMDKVTSDETR | ||||||
Compositional bias | 1894-1911 | Polar residues | ||||
Sequence: TDLIAQRSSDSEEAFETP | ||||||
Region | 1894-1990 | Disordered | ||||
Sequence: TDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGT | ||||||
Compositional bias | 1916-1941 | Pro residues | ||||
Sequence: PVKAPPAPPPPPPEVIPEPEVSTQPP | ||||||
Region | 2007-2416 | Disordered | ||||
Sequence: LEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPV | ||||||
Compositional bias | 2026-2054 | Polar residues | ||||
Sequence: KSTDSVPISKSTLSRSLSLQASDFDGASS | ||||||
Compositional bias | 2067-2083 | Polar residues | ||||
Sequence: AYSTGSSSASSTLKRTK | ||||||
Compositional bias | 2121-2135 | Polar residues | ||||
Sequence: GENLASETKTESAKT | ||||||
Compositional bias | 2301-2352 | Polar residues | ||||
Sequence: NFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPAS | ||||||
Compositional bias | 2370-2394 | Basic and acidic residues | ||||
Sequence: LNKPAKKKKTPLKTDTFRVKKSPKR | ||||||
Compositional bias | 2398-2412 | Pro residues | ||||
Sequence: SDPPSQDPTPAATPE | ||||||
Compositional bias | 2510-2543 | Polar residues | ||||
Sequence: QESPVKSSPVRMSESPTPCSGSSFEETEALVNTA | ||||||
Region | 2510-2576 | Disordered | ||||
Sequence: QESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAM | ||||||
Domain | 2620-2820 | Transforming acidic coiled-coil-containing protein C-terminal | ||||
Sequence: FQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI | ||||||
Coiled coil | 2629-2822 | |||||
Sequence: LQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAK |
Sequence similarities
Belongs to the TACC family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,826
- Mass (Da)296,742
- Last updated2008-07-01 v1
- Checksum76DF74FC45E23D71
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-36 | Polar residues | ||||
Sequence: MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQ | ||||||
Compositional bias | 184-198 | Polar residues | ||||
Sequence: QKSSFSFSSGIDQSP | ||||||
Compositional bias | 242-265 | Polar residues | ||||
Sequence: GVASVQVTPEAPAAAQQGTESSAV | ||||||
Compositional bias | 510-543 | Pro residues | ||||
Sequence: QPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESA | ||||||
Compositional bias | 602-632 | Basic and acidic residues | ||||
Sequence: FSSKRDPEVGKDELSKPSSDAESRDHPSSHS | ||||||
Compositional bias | 826-843 | Polar residues | ||||
Sequence: SEKHLQPSQAQPETSIFD | ||||||
Compositional bias | 886-935 | Polar residues | ||||
Sequence: NLPTHGGQEQALGSELQSQLPKGTLSDTPTSSPTDMVWESSLTEESELSA | ||||||
Compositional bias | 985-1000 | Polar residues | ||||
Sequence: CTGQGPNKSQQALADA | ||||||
Compositional bias | 1382-1400 | Polar residues | ||||
Sequence: QDPKQGTSGGVDTSSEQIA | ||||||
Compositional bias | 1547-1561 | Polar residues | ||||
Sequence: SQLERSRQELASGLP | ||||||
Compositional bias | 1798-1822 | Basic and acidic residues | ||||
Sequence: PEPDETHDPKLQHLAPEELHTDRES | ||||||
Compositional bias | 1837-1851 | Basic and acidic residues | ||||
Sequence: DAPRVMDKVTSDETR | ||||||
Compositional bias | 1894-1911 | Polar residues | ||||
Sequence: TDLIAQRSSDSEEAFETP | ||||||
Compositional bias | 1916-1941 | Pro residues | ||||
Sequence: PVKAPPAPPPPPPEVIPEPEVSTQPP | ||||||
Compositional bias | 2026-2054 | Polar residues | ||||
Sequence: KSTDSVPISKSTLSRSLSLQASDFDGASS | ||||||
Compositional bias | 2067-2083 | Polar residues | ||||
Sequence: AYSTGSSSASSTLKRTK | ||||||
Compositional bias | 2121-2135 | Polar residues | ||||
Sequence: GENLASETKTESAKT | ||||||
Compositional bias | 2301-2352 | Polar residues | ||||
Sequence: NFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPAS | ||||||
Compositional bias | 2370-2394 | Basic and acidic residues | ||||
Sequence: LNKPAKKKKTPLKTDTFRVKKSPKR | ||||||
Compositional bias | 2398-2412 | Pro residues | ||||
Sequence: SDPPSQDPTPAATPE | ||||||
Compositional bias | 2510-2543 | Polar residues | ||||
Sequence: QESPVKSSPVRMSESPTPCSGSSFEETEALVNTA |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BC144600 EMBL· GenBank· DDBJ | AAI44601.1 EMBL· GenBank· DDBJ | mRNA | ||
BC150627 EMBL· GenBank· DDBJ | AAI50628.1 EMBL· GenBank· DDBJ | mRNA |