B2RR30 · B2RR30_MOUSE

  • Protein
    Histone acetyltransferase
  • Gene
    Kat2b
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    5/5

Function

Catalytic activity

Features

Showing features for active site, binding site.

1813100200300400500600700800
Type
IDPosition(s)Description
Active site551Proton donor/acceptor
Binding site555-557acetyl-CoA (UniProtKB | ChEBI)
Binding site562-568acetyl-CoA (UniProtKB | ChEBI)
Binding site593-596acetyl-CoA (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentATAC complex
Cellular Componentcentrosome
Cellular Componentcytosol
Cellular Componentnucleoplasm
Molecular Functionchromatin binding
Molecular FunctionDNA-binding transcription factor binding
Molecular Functionhistone acetyltransferase binding
Molecular Functionhistone deacetylase binding
Molecular Functionhistone H3K9 acetyltransferase activity
Molecular Functionlysine N-acetyltransferase activity, acting on acetyl phosphate as donor
Molecular Functiontranscription coactivator activity
Biological Processcellular response to insulin stimulus
Biological Processcellular response to oxidative stress
Biological Processcellular response to parathyroid hormone stimulus
Biological Processinternal peptidyl-lysine acetylation
Biological Processmemory
Biological ProcessN-terminal peptidyl-lysine acetylation
Biological Processnegative regulation of cell population proliferation
Biological Processnegative regulation of centriole replication
Biological Processnegative regulation of rRNA processing
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processpositive regulation of attachment of mitotic spindle microtubules to kinetochore
Biological Processpositive regulation of fatty acid biosynthetic process
Biological Processpositive regulation of neuron projection development
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processvasodilation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Histone acetyltransferase
  • EC number

Gene names

    • Name
      Kat2b

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    B2RR30

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-55Disordered
Compositional bias380-399Polar residues
Region380-423Disordered
Compositional bias409-423Basic and acidic residues
Domain484-632N-acetyltransferase
Domain721-791Bromo

Sequence similarities

Belongs to the acetyltransferase family. GCN5 subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    813
  • Mass (Da)
    91,769
  • Last updated
    2008-07-01 v1
  • MD5 Checksum
    F2DF0E87D0F9EFC2FB47CAB25C8D0BE7
MAEAGGAGSPALPPAPPHGSPRTLATAAGSSASCGPATAVAAAGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRGDLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMDRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPSKERQTTIELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTKVFGRTLLRSVFTIMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSPLGIQTVISPPVTGTALFSSNSTSHEQINGGRTSPGCRGSSGLEANPGEKRKMNNSHAPEEAKRSRVMGDIPVELINEVMSTITDPAGMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHEILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPQIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPKDPEQLYSTLKNILQQVKNHPNAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLRNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCASILEKFFFSKIKEAGLIDK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias380-399Polar residues
Compositional bias409-423Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC138195
EMBL· GenBank· DDBJ
AAI38196.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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