B2R812 · B2R812_HUMAN

  • Protein
    Amiloride-sensitive sodium channel subunit beta
  • Gene
    SCNN1B
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentcytoplasmic vesicle membrane
Cellular Componentexternal side of plasma membrane
Cellular Componentsodium channel complex
Molecular Functionligand-gated sodium channel activity
Molecular FunctionWW domain binding
Biological Processaldosterone metabolic process
Biological Processartery smooth muscle contraction
Biological Processcellular response to aldosterone
Biological Processepithelial fluid transport
Biological Processerythrocyte homeostasis
Biological Processgene expression
Biological Processintracellular sodium ion homeostasis
Biological Processleukocyte activation involved in inflammatory response
Biological Processmucus secretion
Biological Processmulticellular organism growth
Biological Processmulticellular organismal-level water homeostasis
Biological Processneutrophil activation involved in immune response
Biological Processneutrophil-mediated killing of bacterium
Biological Processpotassium ion homeostasis
Biological Processrenal system process
Biological Processresponse to food
Biological Processresponse to xenobiotic stimulus
Biological Processsensory perception of taste
Biological Processsodium ion import across plasma membrane

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Amiloride-sensitive sodium channel subunit beta
  • Alternative names
    • Beta-NaCH
    • Epithelial Na(+) channel subunit beta
    • Nonvoltage-gated sodium channel 1 subunit beta
    • SCNEB

Gene names

    • Name
      SCNN1B
    • ORF names
      hCG_23853

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SCNN1B-VI-T
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    B2R812

Organism-specific databases

Subcellular Location

Apical cell membrane
; Multi-pass membrane protein
Cytoplasmic vesicle membrane
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane50-70Helical

Keywords

Disease & Variants

Organism-specific databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region590-640Disordered
Compositional bias591-605Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    640
  • Mass (Da)
    72,659
  • Last updated
    2008-07-01 v1
  • Checksum
    5249867F0A960E0C
MHVKKYLLKGLHRLQKGPGYTYKELLVWYCDNTNTHGPKRIICEGPKKKAMWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCIGMCKESCNDTQYKMTISMADWPSEASEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITIIKLVALAKSLRQRRAQASYAGPPPTVAELVEAHTNFGFQPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias591-605Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ515831
EMBL· GenBank· DDBJ
ACS13724.1
EMBL· GenBank· DDBJ
Genomic DNA
AK313192
EMBL· GenBank· DDBJ
BAG36009.1
EMBL· GenBank· DDBJ
mRNA
CH471145
EMBL· GenBank· DDBJ
EAW55834.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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