B2NIL0 · B2NIL0_9VERT
- ProteinL-lactate dehydrogenase
- GeneLDH
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids341 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- (S)-lactate + NAD+ = pyruvate + NADH + H+
Pathway
Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 28-33 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 53 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 114 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 137-139 | NAD+ (UniProtKB | ChEBI) | |||
Active site | 194 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | L-lactate dehydrogenase activity | |
Biological Process | lactate metabolic process | |
Biological Process | pyruvate metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameL-lactate dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Cyclostomata > Myxini > Myxiniformes > Myxinidae > Eptatretinae > Eptatretus
Accessions
- Primary accessionB2NIL0
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 22-161 | Lactate/malate dehydrogenase N-terminal | |||
Domain | 164-332 | Lactate/malate dehydrogenase C-terminal | |||
Sequence similarities
Belongs to the LDH/MDH superfamily. LDH family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length341
- Mass (Da)36,909
- Last updated2008-07-01 v1
- MD5 ChecksumE72A66214A63C1E35D654131691C70FE
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB369247 EMBL· GenBank· DDBJ | BAG34678.1 EMBL· GenBank· DDBJ | mRNA |