Lack of periostin leads to suppression of Notch1 and aortic valve disease.Tkatchenko T.V., Tkatchenko A.V., Moreno R., Markwald R.R.Cited forNUCLEOTIDE SEQUENCETissueWhole heartCategorySequencesSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to EMBL/GenBank/DDBJ databases (MAR-2007)Cited in2
Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes.Kuroiwa A., Watanabe T., Hishigaki H., Takahashi E., Namikawa T., Matsuda Y.View abstractCategorySequencesSourceMGI: 109626PubMedEurope PMCCytogenet Cell Genet 81:208-212 (1998)Mapped to99+
A comparative transcriptional map of a region of 250 kb on the human and mouse X chromosome between the G6PD and the FLN1 genes.Rivella S., Tamanini F., Bione S., Mancini M., Herman G., Chatterjee A., Maestrini E., Toniolo D.View abstractCategorySequencesSourceMGI: 109626PubMedEurope PMCGenomics 28:377-382 (1995)Mapped to64
AMPK stimulation inhibits YAP/TAZ signaling to ameliorate hepatic fibrosis.Shihan M.H., Sharma S., Cable C., Prathigudupu V., Chen A., Mattis A.N., Chen J.Y.View abstractAnnotationAMPK stimulation inhibits YAP/TAZ signaling to ameliorate hepatic fibrosis.CategoryPTM / ProcessingSourceGeneRif: 66826PubMedEurope PMCSci Rep 14:5205-5205 (2024)Mapped to12
YAP and TAZ regulate remyelination in the central nervous system.Hong J., Kirkland J.M., Acheta J., Marziali L.N., Beck B., Jeanette H., Bhatia U., Davis G., Herron J.[...], Belin S.View abstractAnnotationYAP and TAZ regulate remyelination in the central nervous system.CategoryFunctionSourceGeneRif: 66826PubMedEurope PMCGlia 72:156-166 (2024)Mapped to9
Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs' Endothelial Corneal Dystrophy.Leonard B.C., Park S., Kim S., Young L.J., Jalilian I., Cosert K., Zhang X., Skeie J.M., Shevalye H.[...], Thomasy S.M.View abstractAnnotationMice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs' Endothelial Corneal Dystrophy.CategorySubcellular LocationSourceGeneRif: 66826, MGI: 109626PubMedEurope PMCInvest Ophthalmol Vis Sci 64:22-22 (2023)Mapped to14
Genetic modifiers modulate phenotypic expression of tafazzin deficiency in a mouse model of Barth syndrome.Wang S., Yazawa E., Keating E.M., Mazumdar N., Hauschild A., Ma Q., Wu H., Xu Y., Shi X.[...], Pu W.T.View abstractCategoryFunctionSourceMGI: 109626PubMedEurope PMCHum Mol Genet 32:2055-2067 (2023)Mapped to13
DELE1 is protective for mitochondrial cardiomyopathy.Huynh H., Zhu S., Lee S., Bao Y., Pang J., Nguyen A., Gu Y., Chen C., Ouyang K.[...], Fang X.View abstractCategoryFunctionSourceMGI: 109626PubMedEurope PMCJ Mol Cell Cardiol 175:44-48 (2023)Mapped to73
Mitochondrial Stress Induces an HRI-eIF2alpha Pathway Protective for Cardiomyopathy.Zhu S., Nguyen A., Pang J., Zhao J., Chen Z., Liang Z., Gu Y., Huynh H., Bao Y.[...], Fang X.CategoryFunctionSourceMGI: 109626PubMedEurope PMCCirculation 146:1028-1031 (2022)Mapped to55
Tafazzin deficiency attenuates anti-cluster of differentiation 40 and interleukin-4 activation of mouse B lymphocytes.Zegallai H.M., Abu-El-Rub E., Mejia E.M., Sparagna G.C., Cole L.K., Marshall A.J., Hatch G.M.View abstractAnnotationTafazzin deficiency attenuates anti-cluster of differentiation 40 and interleukin-4 activation of mouse B lymphocytes.CategoryFunctionSourceGeneRif: 66826PubMedEurope PMCCell Tissue Res 390:429-439 (2022)Mapped to9
Tafazzin deficiency in mouse mesenchymal stem cells promote reprogramming of activated B lymphocytes toward immunosuppressive phenotypes.Zegallai H.M., Abu-El-Rub E., Olayinka-Adefemi F., Cole L.K., Sparagna G.C., Marshall A.J., Hatch G.M.View abstractAnnotationTafazzin deficiency in mouse mesenchymal stem cells promote reprogramming of activated B lymphocytes toward immunosuppressive phenotypes.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 66826, MGI: 109626PubMedEurope PMCFASEB J 36:e22443-e22443 (2022)Mapped to13
Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis.He X., Tolosa M.F., Zhang T., Goru S.K., Ulloa Severino L., Misra P.S., McEvoy C.M., Caldwell L., Szeto S.G.[...], Yuen D.A.View abstractCategoryFunctionSourceMGI: 109626PubMedEurope PMCJCI Insight 7:e146243-e146243 (2022)Mapped to30
A new murine model of Barth syndrome neutropenia links TAFAZZIN deficiency to increased ER stress-induced apoptosis.Sohn J., Milosevic J., Brouse T., Aziz N., Elkhoury J., Wang S., Hauschild A., van Gastel N., Cetinbas M.[...], Sykes D.B.View abstractAnnotationA new murine model of Barth syndrome neutropenia links TAFAZZIN deficiency to increased ER stress-induced apoptosis.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 66826, MGI: 109626PubMedEurope PMCBlood Adv 6:2557-2577 (2022)Mapped to13
Tafazzin deficiency impairs mitochondrial metabolism and function of lipopolysaccharide activated B lymphocytes in mice.Zegallai H.M., Abu-El-Rub E., Cole L.K., Field J., Mejia E.M., Gordon J.W., Marshall A.J., Hatch G.M.View abstractAnnotationTafazzin deficiency impairs mitochondrial metabolism and function of lipopolysaccharide activated B lymphocytes in mice.CategoryFunctionSourceGeneRif: 66826, MGI: 109626PubMedEurope PMCFASEB J 35:e22023-e22023 (2021)Mapped to13
Loss of Mitochondrial Ca<sup>2+</sup> Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy.Bertero E., Nickel A., Kohlhaas M., Hohl M., Sequeira V., Brune C., Schwemmlein J., Abesser M., Schuh K.[...], Maack C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 109626PubMedEurope PMCCirculation 144:1694-1713 (2021)Mapped to13
Cardiolipin Remodeling Defects Impair Mitochondrial Architecture and Function in a Murine Model of Barth Syndrome Cardiomyopathy.Zhu S., Chen Z., Zhu M., Shen Y., Leon L.J., Chi L., Spinozzi S., Tan C., Gu Y.[...], Fang X.View abstractCategoryFunctionSourceMGI: 109626PubMedEurope PMCCirc Heart Fail 14:e008289-e008289 (2021)Mapped to13
Tafazzin Deficiency Reduces Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets From Male Mice.Cole L.K., Agarwal P., Doucette C.A., Fonseca M., Xiang B., Sparagna G.C., Seshadri N., Vandel M., Dolinsky V.W., Hatch G.M.View abstractAnnotationTafazzin Deficiency Reduces Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets From Male Mice.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 66826, MGI: 109626PubMedEurope PMCEndocrinology 162:bqab102-bqab102 (2021)Mapped to13
Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth.Niki Y., Kobayashi Y., Moriyama K.View abstractCategoriesFunction, ExpressionSourceMGI: 109626PubMedEurope PMCGene Expr Patterns 40:119182-119182 (2021)Mapped to80
Tafazzin Modulates Allergen-Induced Mast Cell Inflammatory Mediator Secretion.Maguire A.R.R., Crozier R.W.E., Hunter K.D., Claypool S.M., Fajardo V.A., LeBlanc P.J., MacNeil A.J.View abstractAnnotationTafazzin Modulates Allergen-Induced Mast Cell Inflammatory Mediator Secretion.CategoryFunctionSourceGeneRif: 66826, MGI: 109626PubMedEurope PMCImmunohorizons 5:182-192 (2021)Mapped to13
A mouse model of short-term, diet-induced fatty liver with abnormal cardiolipin remodeling via downregulated Tafazzin gene expression.Sakurai T., Chen Z., Yamahata A., Hayasaka T., Satoh H., Sekiguchi H., Chiba H., Hui S.P.View abstractAnnotationA mouse model of short-term diet-induced fatty liver with abnormal cardiolipin remodeling via downregulated Tafazzin gene expression.CategoryFunctionSourceGeneRif: 66826PubMedEurope PMCJ Sci Food Agric 101:4995-5001 (2021)Mapped to9
Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice.Wang J.J., Ge W., Zhai Q.Y., Liu J.C., Sun X.W., Liu W.X., Li L., Lei C.Z., Dyce P.W.[...], Shen W.View abstractCategoryExpressionSourceMGI: 109626PubMedEurope PMCPLoS Biol 18:e3001025-e3001025 (2020)Mapped to45
Dynamic Cardiolipin Synthesis Is Required for CD8<sup>+</sup> T Cell Immunity.Corrado M., Edwards-Hicks J., Villa M., Flachsmann L.J., Sanin D.E., Jacobs M., Baixauli F., Stanczak M., Anderson E.[...], Pearce E.L.View abstractCategoryFunctionSourceMGI: 109626PubMedEurope PMCCell Metab 32:981-995.e7 (2020)Mapped to16
Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H<sub>2</sub> O<sub>2</sub> production in heart and skeletal muscle mitochondria.Goncalves R.L.S., Schlame M., Bartelt A., Brand M.D., Hotamıslıgil G.S.View abstractAnnotationCardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H2 O2 production in heart and skeletal muscle mitochondria.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 66826, MGI: 109626PubMedEurope PMCFEBS Lett 595:415-432 (2021)Mapped to13
YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling.Cha B., Ho Y.C., Geng X., Mahamud M.R., Chen L., Kim Y., Choi D., Kim T.H., Randolph G.J.[...], Srinivasan R.S.View abstractCategoryFunctionSourceMGI: 109626PubMedEurope PMCDevelopment 147:dev195453-dev195453 (2020)Mapped to46
Tafazzin deficiency impairs CoA-dependent oxidative metabolism in cardiac mitochondria.Le C.H., Benage L.G., Specht K.S., Li Puma L.C., Mulligan C.M., Heuberger A.L., Prenni J.E., Claypool S.M., Chatfield K.C.[...], Chicco A.J.View abstractAnnotationTafazzin deficiency impairs CoA-dependent oxidative metabolism in cardiac mitochondria.CategoryFunctionSourceGeneRif: 66826, MGI: 109626PubMedEurope PMCJ Biol Chem 295:12485-12497 (2020)Mapped to13