B2JDT0 · PDXH_PARP8
- ProteinPyridoxine/pyridoxamine 5'-phosphate oxidase
- GenepdxH
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids212 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
Catalytic activity
- pyridoxamine 5'-phosphate + O2 + H2O = pyridoxal 5'-phosphate + H2O2 + NH4+
Cofactor
Note: Binds 1 FMN per subunit.
Pathway
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 8-11 | substrate | |||
Binding site | 61-66 | FMN (UniProtKB | ChEBI) | |||
Binding site | 66 | substrate | |||
Binding site | 76-77 | FMN (UniProtKB | ChEBI) | |||
Binding site | 82 | FMN (UniProtKB | ChEBI) | |||
Binding site | 83 | FMN (UniProtKB | ChEBI) | |||
Binding site | 105 | FMN (UniProtKB | ChEBI) | |||
Binding site | 123 | substrate | |||
Binding site | 127 | substrate | |||
Binding site | 131 | substrate | |||
Binding site | 140-141 | FMN (UniProtKB | ChEBI) | |||
Binding site | 184 | FMN (UniProtKB | ChEBI) | |||
Binding site | 190-192 | substrate | |||
Binding site | 194 | FMN (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | FMN binding | |
Molecular Function | pyridoxamine phosphate oxidase activity | |
Biological Process | pyridoxine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyridoxine/pyridoxamine 5'-phosphate oxidase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia
Accessions
- Primary accessionB2JDT0
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000186296 | 1-212 | Pyridoxine/pyridoxamine 5'-phosphate oxidase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length212
- Mass (Da)23,982
- Last updated2008-06-10 v1
- ChecksumB1066542F52733C3
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001043 EMBL· GenBank· DDBJ | ACC69706.1 EMBL· GenBank· DDBJ | Genomic DNA |