B2I029 · RNPH_ACIBC

Function

function

Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

Catalytic activity

Features

Showing features for binding site.

123820406080100120140160180200220
TypeIDPosition(s)Description
Binding site86phosphate (UniProtKB | ChEBI); substrate
Binding site124-126phosphate (UniProtKB | ChEBI); substrate

GO annotations

AspectTerm
Molecular Function3'-5'-RNA exonuclease activity
Molecular FunctiontRNA binding
Molecular FunctiontRNA nucleotidyltransferase activity
Biological ProcessrRNA catabolic process
Biological ProcessrRNA processing
Biological ProcesstRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease PH
  • EC number
  • Short names
    RNase PH
  • Alternative names
    • tRNA nucleotidyltransferase

Gene names

    • Name
      rph
    • Ordered locus names
      ACICU_00063

Organism names

  • Taxonomic identifier
  • Strain
    • ACICU
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex

Accessions

  • Primary accession
    B2I029

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001293081-238Ribonuclease PH

Interaction

Subunit

Homohexameric ring arranged as a trimer of dimers.

Structure

Family & Domains

Sequence similarities

Belongs to the RNase PH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    238
  • Mass (Da)
    26,296
  • Last updated
    2008-06-10 v1
  • MD5 Checksum
    F429E7AAB9B18312A2EBC6E01958CCE5
MRIDQRALDQLREVKITRNYTRYAEGSVLVEFGHTKVLCTASIDNSVPRFLKGQGQGWVTAEYGMLPRSTHSRCDREAARGKQTGRTQEIQRLIGRSLRAMVDLKKLGENTITIDCDVIQADGGTRTASITGAAVALVDAMNVLLAQKKIKQDPLKGLVAAISVGMYQDEVLLDLCYEEDSNCQTDLNVVMTQAGEFIEIQGTAEDKPFTRAQSNAMLEMAEKGIAELIKKQQEALGW

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000863
EMBL· GenBank· DDBJ
ACC55375.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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