B2HSL2 · EFG_MYCMM
- ProteinElongation factor G
- GenefusA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids701 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 20-27 | GTP (UniProtKB | ChEBI) | |||
Binding site | 84-88 | GTP (UniProtKB | ChEBI) | |||
Binding site | 138-141 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | translation elongation factor activity | |
Biological Process | ribosome disassembly |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameElongation factor G
- Short namesEF-G
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillati > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium > Mycobacterium ulcerans group
Accessions
- Primary accessionB2HSL2
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 11-287 | tr-type G | |||
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length701
- Mass (Da)76,965
- Last updated2008-06-10 v1
- MD5 Checksum141203DA19AB9362F4E33D3030965EDC
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000854 EMBL· GenBank· DDBJ | ACC39470.1 EMBL· GenBank· DDBJ | Genomic DNA |