B2GKG9 · MIAA_KOCRD

Function

function

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i6A).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, site.

131320406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site20-27ATP (UniProtKB | ChEBI)
Binding site22-27substrate
Site111Interaction with substrate tRNA
Site132Interaction with substrate tRNA

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctiontRNA dimethylallyltransferase activity
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA dimethylallyltransferase
  • EC number
  • Alternative names
    • Dimethylallyl diphosphate:tRNA dimethylallyltransferase
      (DMAPP:tRNA dimethylallyltransferase
      ; DMATase
      )
    • Isopentenyl-diphosphate:tRNA isopentenyltransferase
      (IPP transferase
      ; IPPT
      ; IPTase
      )

Gene names

    • Name
      miaA
    • Ordered locus names
      KRH_15810

Organism names

Accessions

  • Primary accession
    B2GKG9

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003771951-313tRNA dimethylallyltransferase

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the IPP transferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    313
  • Mass (Da)
    34,331
  • Last updated
    2008-06-10 v1
  • Checksum
    F39C134E5CE81678
MSAPDAGREDTRIPLVAVVGPTGTGKSELAIALARELDGEVVNADALQLYRGMDVGTAKLTPEERQGVPHHLLDVLEIHEEASVAAFQRDARRAVDEIRGRGRVPVLVGGSGLYVRAALDAIEFPGTDATVRARREEQLRERGRAALLRELAAVDPGSAERVKDDRRLVRALEVHDLTGRPFTSFMPERRYVQPTVQIGLAMDREVLNRRLAHRVDLMLERGWLEEVKALEARGLRESPTAGRALGYPQLLAVLDGSATLDEAREDTVAATRRFTKRQRTWFGADPRVHWLDAGDPNGIDGLTAGAVRLVAAQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP009152
EMBL· GenBank· DDBJ
BAG29928.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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