B2GBS2 · SERC_LIMF3
- ProteinPhosphoserine aminotransferase
- GeneserC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids357 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Catalytic activity
- O-phospho-L-serine + 2-oxoglutarate = 3-phosphooxypyruvate + L-glutamate
Cofactor
Note: Binds 1 pyridoxal phosphate per subunit.
Pathway
Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 41 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 76-77 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 102 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 152 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 171 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 194 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
Binding site | 235-236 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | O-phospho-L-serine:2-oxoglutarate aminotransferase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | L-serine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoserine aminotransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Limosilactobacillus
Accessions
- Primary accessionB2GBS2
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000097215 | 1-357 | Phosphoserine aminotransferase | ||
Modified residue | 195 | N6-(pyridoxal phosphate)lysine | |||
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length357
- Mass (Da)39,457
- Last updated2008-06-10 v1
- MD5 Checksum8D2ABD0FE4403612C7CCFCB10FE9CB04
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP008937 EMBL· GenBank· DDBJ | BAG27104.1 EMBL· GenBank· DDBJ | Genomic DNA |