B2ANA6 · B2ANA6_PODAN
- ProteinIsocitrate lyase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids608 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate
Cofactor
Note: Can also use Mn2+ ion.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 165-167 | substrate | |||
Binding site | 236 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 274 | Proton acceptor | |||
Binding site | 275-276 | substrate | |||
Binding site | 311 | substrate | |||
Binding site | 493-497 | substrate | |||
Binding site | 528 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial matrix | |
Molecular Function | isocitrate lyase activity | |
Molecular Function | metal ion binding | |
Molecular Function | methylisocitrate lyase activity | |
Biological Process | propionate catabolic process, 2-methylcitrate cycle |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameIsocitrate lyase
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Sordariomycetidae > Sordariales > Podosporaceae > Podospora > Podospora anserina
Accessions
- Primary accessionB2ANA6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length608
- Mass (Da)66,684
- Last updated2008-05-20 v1
- Checksum44527A9F48006BB8
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CU633872 EMBL· GenBank· DDBJ | CAP65505.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FO904941 EMBL· GenBank· DDBJ | CDP31500.1 EMBL· GenBank· DDBJ | Genomic DNA |