B1W6Z3 · B1W6Z3_HUMAN

  • Protein
    NADH-ubiquinone oxidoreductase chain 3
  • Gene
    NADH3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 3
  • EC number

Gene names

    • Name
      NADH3
    • Synonyms
      ND3

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • SCsq0028
    • SCsq0060
    • AP6/M51
    • Hte64/M51
    • ThE14/M51
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    B1W6Z3

Subcellular Location

Membrane
Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-24Helical
Transmembrane55-78Helical
Transmembrane84-107Helical

Keywords

PTM/Processing

Proteomic databases

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. Interacts with TMEM186. Interacts with TMEM242.

Family & Domains

Sequence similarities

Belongs to the complex I subunit 3 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    115
  • Mass (Da)
    13,186
  • Last updated
    2008-05-20 v1
  • Checksum
    FA827C13A5118EE6
MNFALILMINTLLALLLMIITFWLPQLNGYMEKSTPYECGFDPMSPARVPFSMKFFLVAITFLLFDLEIALLLPLPWALQTTNLPLMVMSSLLLIIILALSLTYEWLQKGLDWAE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ383459
EMBL· GenBank· DDBJ
ACM73100.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383460
EMBL· GenBank· DDBJ
ACM73113.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383461
EMBL· GenBank· DDBJ
ACM73126.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383462
EMBL· GenBank· DDBJ
ACM73139.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383463
EMBL· GenBank· DDBJ
ACM73152.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383464
EMBL· GenBank· DDBJ
ACM73165.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383465
EMBL· GenBank· DDBJ
ACM73178.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383466
EMBL· GenBank· DDBJ
ACM73191.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383467
EMBL· GenBank· DDBJ
ACM73204.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383468
EMBL· GenBank· DDBJ
ACM73217.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383469
EMBL· GenBank· DDBJ
ACM73230.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383470
EMBL· GenBank· DDBJ
ACM73243.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383471
EMBL· GenBank· DDBJ
ACM73256.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383472
EMBL· GenBank· DDBJ
ACM73269.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383473
EMBL· GenBank· DDBJ
ACM73282.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383474
EMBL· GenBank· DDBJ
ACM73295.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383475
EMBL· GenBank· DDBJ
ACM73308.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383476
EMBL· GenBank· DDBJ
ACM73321.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383477
EMBL· GenBank· DDBJ
ACM73334.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383478
EMBL· GenBank· DDBJ
ACM73347.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383479
EMBL· GenBank· DDBJ
ACM73360.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383480
EMBL· GenBank· DDBJ
ACM73373.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383481
EMBL· GenBank· DDBJ
ACM73386.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383482
EMBL· GenBank· DDBJ
ACM73399.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383483
EMBL· GenBank· DDBJ
ACM73412.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383484
EMBL· GenBank· DDBJ
ACM73425.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ383485
EMBL· GenBank· DDBJ
ACM73438.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ770942
EMBL· GenBank· DDBJ
ACN49519.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ770965
EMBL· GenBank· DDBJ
ACN49818.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ770972
EMBL· GenBank· DDBJ
ACN49908.1
EMBL· GenBank· DDBJ
Genomic DNA
GQ337662
EMBL· GenBank· DDBJ
ACU11179.1
EMBL· GenBank· DDBJ
Genomic DNA
JX462722
EMBL· GenBank· DDBJ
AFU89749.1
EMBL· GenBank· DDBJ
Genomic DNA
JX462733
EMBL· GenBank· DDBJ
AFU89892.1
EMBL· GenBank· DDBJ
Genomic DNA
KC990681
EMBL· GenBank· DDBJ
AGV04479.1
EMBL· GenBank· DDBJ
Genomic DNA
KP017257
EMBL· GenBank· DDBJ
AJD85394.1
EMBL· GenBank· DDBJ
Genomic DNA
KR074240
EMBL· GenBank· DDBJ
AKV62402.1
EMBL· GenBank· DDBJ
Genomic DNA
KX467305
EMBL· GenBank· DDBJ
ANU80867.1
EMBL· GenBank· DDBJ
Genomic DNA
AP010688
EMBL· GenBank· DDBJ
BAG14751.1
EMBL· GenBank· DDBJ
Genomic DNA
AP010720
EMBL· GenBank· DDBJ
BAG15167.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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