Identification and molecular characterization of a novel PDE4D11 cAMP- specific phosphodiesterase isoform.Lynex C.N., Li Z., Chen M.L., Toh K.Y., Low R.W., Goh D.L., Tay S.K.View abstractCited forNUCLEOTIDE SEQUENCEStrainSwiss WebsterCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell Signal 20:2247-2255 (2008)Cited in1Mapped to11
Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (AUG-2024)Cited in99+
An integrated genetic map of the pearl locus of mouse chromosome 13.Seymour A.B., Yanak B.L., O'Brien E.P., Rusiniak M.E., Novak E.K., Pinto L.H., Swank R.T., Gorin M.B.View abstractCategorySequencesSourceMGI: 99555PubMedEurope PMCGenome Res 6:538-544 (1996)Mapped to99+
A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons.Cherry J.A., Davis R.L.View abstractCategoriesSequences, ExpressionSourceMGI: 99555PubMedEurope PMCJ Neurobiol 28:102-113 (1995)Mapped to53
Chromosome localizations of genes for five cAMP-specific phosphodiesterases in man and mouse.Milatovich A., Bolger G., Michaeli T., Francke U.View abstractCategorySequencesSourceMGI: 99555PubMedEurope PMCSomat Cell Mol Genet 20:75-86 (1994)Mapped to84
PDE4D mediates impaired beta-adrenergic receptor signalling in the sinoatrial node in mice with hypertensive heart disease.Dorey T.W., McRae M.D., Belke D.D., Rose R.A.View abstractAnnotationPDE4D mediates impaired beta-adrenergic receptor signalling in the sinoatrial node in mice with hypertensive heart disease.CategoryFunctionSourceGeneRif: 238871PubMedEurope PMCCardiovasc Res 119:2697-2711 (2023)Mapped to12
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-beta pathology.Paes D., Schepers M., Willems E., Rombaut B., Tiane A., Solomina Y., Tibbo A., Blair C., Kyurkchieva E.[...], Prickaerts J.View abstractAnnotationAblation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-beta pathology.CategoryFunctionSourceGeneRif: 238871PubMedEurope PMCCell Mol Life Sci 80:178-178 (2023)Mapped to12
Genetic deletion of phosphodiesterase 4D in the liver improves kidney damage in high-fat fed mice: liver-kidney crosstalk.Tao X., Chen C., Huang Z., Lei Y., Wang M., Wang S., Tian D.View abstractAnnotationGenetic deletion of phosphodiesterase 4D in the liver improves kidney damage in high-fat fed mice: liver-kidney crosstalk.CategoryFunctionSourceGeneRif: 238871PubMedEurope PMCCell Death Dis 14:273-273 (2023)Mapped to12
Arrestin-dependent nuclear export of phosphodiesterase 4D promotes GPCR- induced nuclear cAMP signaling required for learning and memory.Martinez J.M., Shen A., Xu B., Jovanovic A., de Chabot J., Zhang J., Xiang Y.K.View abstractAnnotationArrestin-dependent nuclear export of phosphodiesterase 4D promotes GPCR-induced nuclear cAMP signaling required for learning and memory.CategoryFunctionSourceGeneRif: 238871PubMedEurope PMCSci Signal 16:eade3380-eade3380 (2023)Mapped to18
Circ_0101874 overexpression strengthens PDE4D expression by targeting miR- 335-5p to promote neuronal injury in ischemic stroke.Pei L., Xu X., Yuan T.View abstractAnnotationCirc_0101874 overexpression strengthens PDE4D expression by targeting miR-335-5p to promote neuronal injury in ischemic stroke.CategoriesFunction, ExpressionSourceGeneRif: 238871PubMedEurope PMCJ Stroke Cerebrovasc Dis 31:106817-106817 (2022)Mapped to12
Phosphodiesterase 4D contributes to angiotensin II-induced abdominal aortic aneurysm through smooth muscle cell apoptosis.Gao R., Guo W., Fan T., Pang J., Hou Y., Feng X., Li B., Ge W., Fan T.[...], Wang J.View abstractAnnotationPhosphodiesterase 4D contributes to angiotensin II-induced abdominal aortic aneurysm through smooth muscle cell apoptosis.CategoriesFunction, ExpressionSourceGeneRif: 238871, MGI: 99555PubMedEurope PMCExp Mol Med 54:1201-1213 (2022)Mapped to24
MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells Through Inhibiting Secretory Protein FAM19A1.Zhang Y.F., Li X.X., Cao X.L., Ji C.C., Gao X.Y., Gao D., Han H., Yu F., Zheng M.H.View abstractCategoryFunctionSourceMGI: 99555PubMedEurope PMCFront Cell Neurosci 16:866020-866020 (2022)Mapped to40
Phosphodiesterase 4D promotes angiotensin II-induced hypertension in mice via smooth muscle cell contraction.Fan T., Hou Y., Ge W., Fan T., Feng X., Guo W., Song X., Gao R., Wang J.View abstractCategoryFunctionSourceMGI: 99555PubMedEurope PMCCommun Biol 5:81-81 (2022)Mapped to22
FGF1 and insulin control lipolysis by convergent pathways.Sancar G., Liu S., Gasser E., Alvarez J.G., Moutos C., Kim K., van Zutphen T., Wang Y., Huddy T.F.[...], Evans R.M.View abstractCategoryFunctionSourceMGI: 99555PubMedEurope PMCCell Metab 34:171-183.e6 (2022)Mapped to33
Assessment of PDE4 Inhibitor-Induced Hypothermia as a Correlate of Nausea in Mice.Boyd A., Aragon I.V., Rich J., McDonough W., Oditt M., Irelan D., Fiedler E., Abou Saleh L., Richter W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 99555PubMedEurope PMCBiology (Basel) 10:1355-1355 (2021)Mapped to44
Genetic Modulation of Initial Sensitivity to Delta9-Tetrahydrocannabinol (THC) Among the BXD Family of Mice.Parks C., Rogers C.M., Prins P., Williams R.W., Chen H., Jones B.C., Moore B.M., Mulligan M.K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 99555PubMedEurope PMCFront Genet 12:659012-659012 (2021)Mapped to40
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.Bedogni F., Hevner R.F.View abstractCategoryPTM / ProcessingSourceMGI: 99555PubMedEurope PMCFront Mol Neurosci 14:686034-686034 (2021)Mapped to99+
The cAMP-phosphodiesterase 4 (PDE4) controls beta-adrenoceptor- and CFTR- dependent saliva secretion in mice.Boyd A., Aragon I.V., Abou Saleh L., Southers D., Richter W.View abstractCategoryFunctionSourceMGI: 99555PubMedEurope PMCBiochem J 478:1891-1906 (2021)Mapped to49
Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice.Aragon I.V., Boyd A., Abou Saleh L., Rich J., McDonough W., Koloteva A., Richter W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 99555PubMedEurope PMCBiochem Pharmacol 186:114477-114477 (2021)Mapped to44
Dominant-Negative Attenuation of cAMP-Selective Phosphodiesterase PDE4D Action Affects Learning and Behavior.Bolger G.B., Smoot L.H.M., van Groen T.View abstractAnnotationDominant-Negative Attenuation of cAMP-Selective Phosphodiesterase PDE4D Action Affects Learning and Behavior.CategoriesFunction, InteractionSourceGeneRif: 238871, MGI: 99555PubMedEurope PMCInt J Mol Sci 21:E5704-E5704 (2020)Mapped to17
PAN-selective inhibition of cAMP-phosphodiesterase 4 (PDE4) induces gastroparesis in mice.McDonough W., Aragon I.V., Rich J., Murphy J.M., Abou Saleh L., Boyd A., Koloteva A., Richter W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 99555PubMedEurope PMCFASEB J 34:12533-12548 (2020)Mapped to44
Upregulation of miR-219a-5p Decreases Cerebral Ischemia/Reperfusion Injury In Vitro by Targeting Pde4d.Lu M.Y., Wu J.R., Liang R.B., Wang Y.P., Zhu Y.C., Ma Z.T., Zhang H., Zan J., Tan W.View abstractAnnotationUpregulation of miR-219a-5p Decreases Cerebral Ischemia/Reperfusion Injury In Vitro by Targeting Pde4d.CategoriesFunction, ExpressionSourceGeneRif: 238871PubMedEurope PMCJ Stroke Cerebrovasc Dis 29:104801-104801 (2020)Mapped to12