B1J3Q4 · TRMA_PSEPW

Function

function

Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

Catalytic activity

Features

Showing features for binding site, active site.

136150100150200250300350
TypeIDPosition(s)Description
Binding site185S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site213S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site218S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site234S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site294S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site319Nucleophile
Active site353Proton acceptor

GO annotations

AspectTerm
Molecular FunctiontRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent
Biological ProcesstRNA methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA/tmRNA (uracil-C(5))-methyltransferase
  • EC number
  • Alternative names
    • tRNA (uracil(54)-C(5))-methyltransferase
    • tRNA(m5U54)-methyltransferase
      (RUMT
      )
    • tmRNA (uracil(341)-C(5))-methyltransferase

Gene names

    • Name
      trmA
    • Ordered locus names
      PputW619_0784

Organism names

Accessions

  • Primary accession
    B1J3Q4

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001985491-361tRNA/tmRNA (uracil-C5)-methyltransferase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    361
  • Mass (Da)
    40,897
  • Last updated
    2008-04-29 v1
  • Checksum
    BC3B6B858AA85B62
MSAAFDPSAYDAQLQAKVTRLRELLAPFGAPQPAVFDSPREHYRLRAEFRLWREDGQRHYAMFAPGEKHKAILIDDFPIASERINALMPRLKAAWQASDELSNRLFQVEFLTTLAGDAMVTMCYHRPLDDAWEVAARQLAEELGVSLIGRSKGKRLVIGRDYAVEKLDVAGRVFSYRQPEGAFTQPNGAVNQKMLSWAYDAIGERDDDLLELYCGNGNFTLPLATRVRQVLATEISKTSVNAALSNLSENAVDNVRLVRLSAEELTQALNEVRPFRRLEGIDLKSYAFGTVFVDPPRAGMDPDTCELTRRFERILYISCNPETLAQNISQLQDTHRIERCALFDQFPYTHHMESGVLLVRR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000949
EMBL· GenBank· DDBJ
ACA71289.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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