B1H325 · B1H325_XENTR

Function

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for binding site, active site.

1783100200300400500600700
Type
IDPosition(s)Description
Binding site333Zn2+ (UniProtKB | ChEBI); catalytic
Active site334
Binding site337Zn2+ (UniProtKB | ChEBI); catalytic
Binding site343Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processproteolysis

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • ADAM metallopeptidase domain 28, gene 2 precursor
    • LOC100145537 protein
    • Metalloproteinase ADAM28b

Gene names

    • Name
      adam28.2
    • Synonyms
      adam28
      , disintegrin
      , LOC100145537

Organism names

Accessions

  • Primary accession
    B1H325

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane653-673Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-22
ChainPRO_503320750223-783
Disulfide bond308↔388
Disulfide bond348↔372
Disulfide bond350↔355
Disulfide bond459↔479

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain197-393Peptidase M12B
Domain401-487Disintegrin
Region697-783Disordered
Compositional bias719-733Pro residues
Compositional bias754-774Pro residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    783
  • Mass (Da)
    86,367
  • Last updated
    2008-04-29 v1
  • Checksum
    C614F218C7915866
MAQAVVPTTLLLSVLLTGHILAFDRIPPGQKYEVVFPKKLHFQQKRDTQSKYPSTVHYEVQLEGEPLVLKLEKTEDLISEHYTETQYLPDGTPIETSPEIQDHCYYQGGVENDSSSLLSISACSGLSGIIQTRGRRYLIEPLKQTDSEEHAVFPYQAQESTPVTCGVTNTTYMEGNFSKTSLATSNAAKVEFLKSKKYIELYMVADKSMFNKYGRSTENVKRRIFEIVNFVNVVYKQINIFVALTGIEVWDKSDGFTVVSSADEDLKLFSDWRTKNLLPRKAHDNAQFITHIDFDGSTVGLAYVGTMCSSTSSTGVIQDHSQQSIAIGATVAHEMGHNLGINHDEAHCTCSTGSCIMEPALSFNTPREFSLCSHQNYQDFILQKMPLCMKDVPKKTEIQTPPVCGNKFTELGEECDCGSISECTNPCCNATTCKLKAGAQCAEGQCCDSCKWTKAGTVCRSKRHDCDLAEMCDGQSAECPSDRFRVNGFPCRNGEGYCYNGLCPTLQGLCSALWGPSSVVADDSCFNYNLRGANNGYCQDSKGNQVPCKQSDVKCGVLYCSGGYSTPNLGGYYIRGECKTTLYPTFLVENGTKCGDNMVCFMGECTSIQTAFGPSDCDAKCPEHAVCDHENQCRCEEGWAPPDCANFTGTNTIIVVVAIICVIVLFILLFVWFKWSSRRKQRTSRTRVTGAVNPAFNVREKPWGPAGSNAATPQLDSRFPHNPPKPPAQSQKPLATHPPTGRSWPQTQVGYPVRPVNAPPPLPTTKPAYPRAPPQAWTPNYRN

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias719-733Pro residues
Compositional bias754-774Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC161221
EMBL· GenBank· DDBJ
AAI61221.1
EMBL· GenBank· DDBJ
mRNA
HM467828
EMBL· GenBank· DDBJ
ADK56771.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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