B1H1H3 · ZDH21_DANRE

Function

function

Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates.

Catalytic activity

Features

Showing features for active site.

126320406080100120140160180200220240260
TypeIDPosition(s)Description
Active site120S-palmitoyl cysteine intermediate

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum
Cellular ComponentGolgi apparatus
Cellular ComponentGolgi membrane
Cellular Componentplasma membrane
Molecular Functionprotein-cysteine S-palmitoyltransferase activity
Biological Processpeptidyl-L-cysteine S-palmitoylation
Biological Processprotein targeting to membrane

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Palmitoyltransferase ZDHHC21
  • EC number
  • Alternative names
    • DHHC domain-containing cysteine-rich protein 21
    • Zinc finger DHHC domain-containing protein 21

Gene names

    • Name
      zdhhc21
    • Synonyms
      dhcc21
    • ORF names
      zgc:158420

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    B1H1H3
  • Secondary accessions
    • A0A2R8RMA6

Proteomes

Organism-specific databases

Subcellular Location

Golgi apparatus membrane
; Multi-pass membrane protein
Golgi apparatus, cis-Golgi network membrane
; Multi-pass membrane protein
Cell membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-4Cytoplasmic
Transmembrane5-25Helical
Topological domain26-44Extracellular
Transmembrane45-65Helical
Topological domain66-131Cytoplasmic
Transmembrane132-152Helical
Topological domain153-181Extracellular
Transmembrane182-202Helical
Topological domain203-263Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004511631-263Palmitoyltransferase ZDHHC21

Keywords

Proteomic databases

Expression

Developmental stage

Probably maternally supplied, the zygotic expression becomes significant at 4.0 hpf and remains constant until 24 hpf.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain90-140DHHC

Domain

The DHHC domain is required for palmitoyltransferase activity.

Sequence similarities

Belongs to the DHHC palmitoyltransferase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    263
  • Mass (Da)
    30,916
  • Last updated
    2020-10-07 v2
  • Checksum
    70603A619F936071
MKMRLHFVVDPMGWFCMSMVFFVWIYNSFLIPKLVLLPHYAEGHITAEPVICYYLASLLCFSALFRASTTDPGKLAQDPKIPLAERDNWELCNKCNMMRPKRSHHCSRCGHCVRRMDHHCPWINNCVGEDNHWLFLQLCFYTQVLSFYTLVLDFCQYYYFLPLSSVDQADFAVHHELALLRVSCFMGLIMFGGISSLFYTQVKGILTDTTTIEKMSHLTEEVPRRPWQQAMAEVFGTRWKVLWFLPFRSRHPLKLNLTIRSHV

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict254in Ref. 1; AAI60605

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC160605
EMBL· GenBank· DDBJ
AAI60605.1
EMBL· GenBank· DDBJ
mRNA
CABZ01067984
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CR536621
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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