B1AXJ4 · B1AXJ4_MOUSE
- ProteinLow density lipoprotein receptor-related protein 8, apolipoprotein e receptor
- GeneLrp8
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids955 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | calcium ion binding | |
Biological Process | endocytosis |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionB1AXJ4
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 817-840 | Helical | ||||
Sequence: AAVIGVIVPIVVIALLCMSGYLIW |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MGRPELGALRPLALLLLLLLQLQHLSA | ||||||
Chain | PRO_5002761947 | 28-955 | ||||
Sequence: ADPLPGGQGPVKECEEDQFRCRNERCIPLVWRCDEDNDCSDNSDEDDCPKRTCADSDFTCDNGHCIPERWKCDGEEECPDGSDESKATCSSEECPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCPTLCAPHEFQCSNRSCLASVFVCDGDDDCGDGSDERGCSDPACPPREFRCGGGGTCIPERWVCDRQFDCEDRSDEAAELCGRAGQGTTATPAACAPTAQFTCRSGECIHLGWRCDGDRDCKDKSDEADCSPGPCRENEFQCGDGTCVLAIKRCNQERDCPDGSDEAGCLQGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECQDPDACSQICVNYKGYFKCECHPGYEMDTLTKNCKAVAGKSPSLIFTNRHEVRRIDLVKRDYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAHMDKASIPDEQVVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATTDGRRRCTLFSRELSEPRAIAVDPLRGFMYWSDWGFQAKIEKAGLNGADRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFNGGNRKMLIFSTDFLSHPFGVAVFEDKVFWTDLENEAIFSANRLNGLEIAILAENLNNPHDIVIFHELKQPKAADACDLSAQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRAPQSTSTTTLASAMTRTVPATTRAPGTTIHDPTYQNHSTETPSQTAAAPHSVNVPRAPSTSPSTPSPATSNHSQHYGNEGSQMGSTVTAAVIGVIVPIVVIALLCMSGYLIWRNWKRKNTKSMNFDNPVYRKTTEEEEEDELHIGRTAQIGHVYPAAISNYDRPLWAEPCLGETRDLEDPAPALKELFVLPGEPRSQLHQLPKNPLSELPVVKCKRVALSLEDDGLP | ||||||
Disulfide bond | 41↔53 | |||||
Sequence: CEEDQFRCRNERC | ||||||
Disulfide bond | 48↔66 | |||||
Sequence: CRNERCIPLVWRCDEDNDC | ||||||
Disulfide bond | 60↔75 | |||||
Sequence: CDEDNDCSDNSDEDDC | ||||||
Disulfide bond | 80↔92 | |||||
Sequence: CADSDFTCDNGHC | ||||||
Disulfide bond | 87↔105 | |||||
Sequence: CDNGHCIPERWKCDGEEEC | ||||||
Disulfide bond | 142↔157 | |||||
Sequence: CDGEKDCEGGADEAGC | ||||||
Disulfide bond | 161↔173 | |||||
Sequence: CAPHEFQCSNRSC | ||||||
Disulfide bond | 168↔186 | |||||
Sequence: CSNRSCLASVFVCDGDDDC | ||||||
Disulfide bond | 180↔195 | |||||
Sequence: CDGDDDCGDGSDERGC | ||||||
Disulfide bond | 259↔277 | |||||
Sequence: CRSGECIHLGWRCDGDRDC | ||||||
Disulfide bond | 271↔286 | |||||
Sequence: CDGDRDCKDKSDEADC | ||||||
Disulfide bond | 291↔303 | |||||
Sequence: CRENEFQCGDGTC | ||||||
Disulfide bond | 298↔316 | |||||
Sequence: CGDGTCVLAIKRCNQERDC | ||||||
Disulfide bond | 310↔325 | |||||
Sequence: CNQERDCPDGSDEAGC | ||||||
Disulfide bond | 372↔382 | |||||
Sequence: CQDPDACSQIC |
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, repeat, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 368-407 | EGF-like | ||||
Sequence: DIDECQDPDACSQICVNYKGYFKCECHPGYEMDTLTKNCK | ||||||
Repeat | 454-500 | LDL-receptor class B | ||||
Sequence: NRIYWCDLSYRKIYSAHMDKASIPDEQVVLIDEQLHSPEGLAVDWVH | ||||||
Repeat | 501-543 | LDL-receptor class B | ||||
Sequence: KHIYWTDSGNKTISVATTDGRRRCTLFSRELSEPRAIAVDPLR | ||||||
Repeat | 544-587 | LDL-receptor class B | ||||
Sequence: GFMYWSDWGFQAKIEKAGLNGADRQTLVSDNIEWPNGITLDLLS | ||||||
Repeat | 588-632 | LDL-receptor class B | ||||
Sequence: QRLYWVDSKLHQLSSIDFNGGNRKMLIFSTDFLSHPFGVAVFEDK | ||||||
Region | 737-810 | Disordered | ||||
Sequence: TLASAMTRTVPATTRAPGTTIHDPTYQNHSTETPSQTAAAPHSVNVPRAPSTSPSTPSPATSNHSQHYGNEGSQ |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length955
- Mass (Da)105,183
- Last updated2008-04-08 v1
- Checksum76D204FDC5756458
Computationally mapped potential isoform sequences
There are 12 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q924X6 | LRP8_MOUSE | Lrp8 | 996 | ||
B1AXJ3 | B1AXJ3_MOUSE | Lrp8 | 832 | ||
B1AXJ5 | B1AXJ5_MOUSE | Lrp8 | 896 | ||
B1AXJ6 | B1AXJ6_MOUSE | Lrp8 | 694 | ||
F6YZZ8 | F6YZZ8_MOUSE | Lrp8 | 870 | ||
A0A571BEC8 | A0A571BEC8_MOUSE | Lrp8 | 726 | ||
A0A571BE80 | A0A571BE80_MOUSE | Lrp8 | 787 | ||
A0A571BE60 | A0A571BE60_MOUSE | Lrp8 | 828 | ||
A0A571BDQ2 | A0A571BDQ2_MOUSE | Lrp8 | 135 | ||
A0A571BDC7 | A0A571BDC7_MOUSE | Lrp8 | 189 | ||
A0A571BGD2 | A0A571BGD2_MOUSE | Lrp8 | 157 | ||
A0A571BEF2 | A0A571BEF2_MOUSE | Lrp8 | 124 |
Keywords
- Technical term