B1AXF5 · B1AXF5_MOUSE
- ProteinAlkaline phosphatase, tissue-nonspecific isozyme
- GeneAlpl
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids157 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
Catalytic activity
- ADP + H2O = AMP + H+ + phosphateThis reaction proceeds in the forward direction.
- AMP + H2O = adenosine + phosphateThis reaction proceeds in the forward direction.
- ATP + H2O = ADP + H+ + phosphateThis reaction proceeds in the forward direction.
- H2O + phosphoethanolamine = ethanolamine + phosphateThis reaction proceeds in the forward direction.
- H2O + pyridoxal 5'-phosphate = phosphate + pyridoxalThis reaction proceeds in the forward direction.
- diphosphate + H2O = H+ + 2 phosphateThis reaction proceeds in the forward direction.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 Mg2+ ion.
Note: Binds 2 Zn2+ ions.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial intermembrane space | |
Cellular Component | mitochondrial membrane | |
Cellular Component | plasma membrane | |
Cellular Component | side of membrane | |
Molecular Function | alkaline phosphatase activity | |
Molecular Function | metal ion binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlkaline phosphatase, tissue-nonspecific isozyme
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionB1AXF5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Lipid-anchor, GPI-anchor
Extracellular vesicle membrane ; Lipid-anchor, GPI-anchor
Membrane ; Lipid-anchor, GPI-anchor
Mitochondrion membrane ; Lipid-anchor, GPI-anchor
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-17 | |||||
Sequence: MISPFLVLAIGTCLTNS | ||||||
Chain | PRO_5008409944 | 18-157 | Alkaline phosphatase, tissue-nonspecific isozyme | |||
Sequence: FVPEKERDPSYWRQQAQETLKNALKLQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRCNTTQGNEVTSILRWAKDA |
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusFragment
- Length157
- Mass (Da)17,095
- Last updated2016-10-05 v8
- Checksum2AF871099B292CDF
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 157 | |||||
Sequence: A |
Keywords
- Technical term