B1AUD7 · B1AUD7_MOUSE

  • Protein
    P2X purinoceptor
  • Gene
    P2rx5
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Receptor for ATP that acts as a ligand-gated ion channel.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site.

135450100150200250300350
TypeIDPosition(s)Description
Binding site69-71ATP (UniProtKB | ChEBI)
Binding site189ATP (UniProtKB | ChEBI)
Binding site294-296ATP (UniProtKB | ChEBI)
Binding site314ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componentpostsynapse
Molecular FunctionATP binding
Molecular Functionextracellularly ATP-gated monoatomic cation channel activity
Molecular Functionpurinergic nucleotide receptor activity
Biological Processresponse to ATP

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    P2X purinoceptor

Gene names

    • Name
      P2rx5

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    B1AUD7

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane31-51Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond118↔169
Disulfide bond129↔152
Disulfide bond135↔163
Disulfide bond220↔229
Disulfide bond263↔272

Keywords

Proteomic databases

Expression

Gene expression databases

Structure

Family & Domains

Sequence similarities

Belongs to the P2X receptor family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    354
  • Mass (Da)
    40,231
  • Last updated
    2008-04-08 v1
  • Checksum
    3B93744600E68734
MGQAAWKGFVLSLFDYKTAKFVVAKSKKVGLLYRVLQLTILLYLLIWVFLIKKSYQDIDTSLQSAVVTKVKGVAYTNTTMLGERLWDVADFVIPSQGENVFFVVTNLIVTPNQRQGICAEREGIPDGECSEDTDCHAGESVVAGHGLKTGRCLRVGNSTRGTCEIFAWCPVETKSMPTDPLLKDAEGFTIFIKNFIRFPKFNFSKANVLETGNKHFLKTCHFSSTNLYCPIFRLGSIVRWAGADFQDIALKGGVIGIHIEWDCDLDKAASHCNPHYYFNRLDNKHTQSISSGYNFRFARYYRDPHGVEFRDLMKAYGIRFDVIVNGKGAFFCDLVLIYLIRKSEFYRDKKFEKV

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q91VE2P2RX5_MOUSEP2rx5455
B1AUD6B1AUD6_MOUSEP2rx5330

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue354

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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