Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Cloning of a retinoic acid-induced gene, GT1, in the embryonal carcinoma cell line P19: neuron-specific expression in the mouse brain.Imai Y., Suzuki Y., Matsui T., Tohyama M., Wanaka A., Takagi T.View abstractCategoriesSequencesSourceMGI: 103291PubMedEurope PMCBrain Res. Mol. Brain Res. 31:1-9 (1995)Cited in1Mapped to4
Smith-Magenis syndrome protein RAI1 regulates body weight homeostasis through hypothalamic BDNF-producing neurons and neurotrophin downstream signalling.Javed S., Chang Y.T., Cho Y., Lee Y.J., Chang H.C., Haque M., Lin Y.C., Huang W.H.View abstractSourceMGI: 103291PubMedEurope PMCElife 12:RP90333-RP90333 (2023)Mapped to10
rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues selective disease features in Smith-Magenis syndrome mice.Chang H.C., Lee Y.J., Javed S., Haque M., Chang Y.T., Lin Y.C., Oram C., Huang W.H.View abstractCategoriesFunction, ExpressionSourceMGI: 103291PubMedEurope PMCJ Biol Chem 299:102728-102728 (2023)Mapped to5
Disruption of MeCP2-TCF20 complex underlies distinct neurodevelopmental disorders.Zhou J., Hamdan H., Yalamanchili H.K., Pang K., Pohodich A.E., Lopez J., Shao Y., Oses-Prieto J.A., Li L.[...], Zoghbi H.Y.View abstractCategoriesInteractionSourceMGI: 103291PubMedEurope PMCProc Natl Acad Sci U S A 119:e2119078119-e2119078119 (2022)Mapped to41
Temporal dissection of Rai1 function reveals brain-derived neurotrophic factor as a potential therapeutic target for Smith-Magenis syndrome.Javed S., Lee Y.J., Xu J., Huang W.H.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceMGI: 103291PubMedEurope PMCHum Mol Genet 31:275-288 (2021)Mapped to16
Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.Luo L., Ambrozkiewicz M.C., Benseler F., Chen C., Dumontier E., Falkner S., Furlanis E., Gomez A.M., Hoshina N.[...], Craig A.M.View abstractCategoriesFunctionSourceMGI: 103291PubMedEurope PMCNeuron 106:37-65.e5 (2020)Mapped to99+
Early adolescent Rai1 reactivation reverses transcriptional and social interaction deficits in a mouse model of Smith-Magenis syndrome.Huang W.H., Wang D.C., Allen W.E., Klope M., Hu H., Shamloo M., Luo L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 103291PubMedEurope PMCProc Natl Acad Sci U S A 115:10744-10749 (2018)Mapped to15
<i>Rai1</i> frees mice from the repression of active wake behaviors by light.Diessler S., Kostic C., Arsenijevic Y., Kawasaki A., Franken P.View abstractCategoriesFunctionSourceMGI: 103291PubMedEurope PMCElife 6:e23292-e23292 (2017)Mapped to5
Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome.Huang W.H., Guenthner C.J., Xu J., Nguyen T., Schwarz L.A., Wilkinson A.W., Gozani O., Chang H.Y., Shamloo M., Luo L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 103291PubMedEurope PMCNeuron 92:392-406 (2016)Mapped to47
Dietary regimens modify early onset of obesity in mice haploinsufficient for Rai1.Alaimo J.T., Hahn N.C., Hahn N.H., Mullegama S.V., Elsea S.H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 103291PubMedEurope PMCPLoS One 9:e105077-e105077 (2014)Mapped to5
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.Thompson C.L., Ng L., Menon V., Martinez S., Lee C.K., Glattfelder K., Sunkin S.M., Henry A., Lau C.[...], Jones A.R.View abstractCategoriesSequences, ExpressionSourceMGI: 103291PubMedEurope PMCNeuron 83:309-323 (2014)Mapped to99+
Correct developmental expression level of Rai1 in forebrain neurons is required for control of body weight, activity levels and learning and memory.Cao L., Molina J., Abad C., Carmona-Mora P., Cardenas Oyarzo A., Young J.I., Walz K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 103291PubMedEurope PMCHum Mol Genet 23:1771-1782 (2014)Mapped to5
Circadian abnormalities in mouse models of Smith-Magenis syndrome: evidence for involvement of RAI1.Lacaria M., Gu W., Lupski J.R.View abstractCategoriesPhenotypes & VariantsSourceMGI: 103291PubMedEurope PMCAm J Med Genet A 161A:1561-1568 (2013)Mapped to7
The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development.Savino M.T., Ulivieri C., Emmi G., Prisco D., De Falco G., Ortensi B., Beccastrini E., Emmi L., Pelicci G.[...], Baldari C.T.View abstractCategoriesFunctionSourceMGI: 103291PubMedEurope PMCJ Leukoc Biol 93:549-559 (2013)Mapped to10
A duplication CNV that conveys traits reciprocal to metabolic syndrome and protects against diet-induced obesity in mice and men.Lacaria M., Saha P., Potocki L., Bi W., Yan J., Girirajan S., Burns B., Elsea S., Walz K.[...], Gu W.View abstractCategoriesPhenotypes & VariantsSourceMGI: 103291PubMedEurope PMCPLoS Genet 8:e1002713-e1002713 (2012)Mapped to5
Smith-Magenis syndrome results in disruption of CLOCK gene transcription and reveals an integral role for RAI1 in the maintenance of circadian rhythmicity.Williams S.R., Zies D., Mullegama S.V., Grotewiel M.S., Elsea S.H.View abstractCategoriesFunctionSourceMGI: 103291PubMedEurope PMCAm. J. Hum. Genet. 90:941-949 (2012)Cited in2Mapped to17
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.Diez-Roux G., Banfi S., Sultan M., Geffers L., Anand S., Rozado D., Magen A., Canidio E., Pagani M.[...], Ballabio A.View abstractCategoriesExpressionSourceMGI: 103291PubMedEurope PMCPLoS Biol 9:e1000582-e1000582 (2011)Mapped to99+
Phenotypic consequences of copy number variation: insights from Smith- Magenis and Potocki-Lupski syndrome mouse models.Ricard G., Molina J., Chrast J., Gu W., Gheldof N., Pradervand S., Schutz F., Young J.I., Lupski J.R.[...], Walz K.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 103291PubMedEurope PMCPLoS Biol 8:e1000543-e1000543 (2010)Mapped to34
Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome.Burns B., Schmidt K., Williams S.R., Kim S., Girirajan S., Elsea S.H.View abstractCategoriesFunctionSourceMGI: 103291PubMedEurope PMCHum Mol Genet 19:4026-4042 (2010)Mapped to12
Abnormal maternal behavior, altered sociability, and impaired serotonin metabolism in Rai1-transgenic mice.Girirajan S., Elsea S.H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 103291PubMedEurope PMCMamm Genome 20:247-255 (2009)Mapped to5
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.Hansen G.M., Markesich D.C., Burnett M.B., Zhu Q., Dionne K.M., Richter L.J., Finnell R.H., Sands A.T., Zambrowicz B.P., Abuin A.View abstractCategoriesSequencesSourceMGI: 103291PubMedEurope PMCGenome Res 18:1670-1679 (2008)Mapped to99+
How much is too much? Phenotypic consequences of Rai1 overexpression in mice.Girirajan S., Patel N., Slager R.E., Tokarz M.E., Bucan M., Wiley J.L., Elsea S.H.View abstractCategoriesPhenotypes & VariantsSourceMGI: 103291PubMedEurope PMCEur J Hum Genet 16:941-954 (2008)Mapped to5