Longitudinal microcomputed tomography (muCT) imaging and histopathological analyses revealed an increased rate of cyst formation increased proportion of cysts with proliferating cells higher frequency of atypical cysts as well as the development of neoplasms in Vhl/Kif3a/Trp53 mutant kidneys compared to Kif3a/Trp53 or Vhl/Kif3a mutant kidneys.
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