B0Z6G1 · B0Z6G1_DANRE
- ProteinInsulin-like growth factor 3
- Geneigf3
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids188 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | extracellular space | |
Molecular Function | growth factor activity | |
Molecular Function | hormone activity | |
Molecular Function | insulin-like growth factor receptor binding | |
Biological Process | cell population proliferation | |
Biological Process | female sex differentiation | |
Biological Process | insulin-like growth factor receptor signaling pathway | |
Biological Process | negative regulation of apoptotic process | |
Biological Process | oocyte maturation | |
Biological Process | positive regulation of cell population proliferation | |
Biological Process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | |
Biological Process | regulation of female gonad development | |
Biological Process | regulation of oogenesis | |
Biological Process | regulation of protein phosphorylation | |
Biological Process | sperm capacitation |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionB0Z6G1
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-43 | |||||
Sequence: MPTCHAKRLQIMPGFMLKVPSWRSVCVLYSLCCVLILPDNTEG | ||||||
Chain | PRO_5010104725 | 44-188 | ||||
Sequence: ARARCGRELVDDLEFVCGDRGFYIGKPGAARSGGPRSRGKGIVDQCCVRGCDLQHLELYCAKSKKVRRDVPASVLQTPEDQFWLVFQRRYQKLADLQRDEESASQRIRERTLYQQNLLNTKTSTQTSSTHLSSTTETPTFISHIR | ||||||
Disulfide bond | 48↔90 | |||||
Sequence: CGRELVDDLEFVCGDRGFYIGKPGAARSGGPRSRGKGIVDQCC | ||||||
Disulfide bond | 60↔103 | |||||
Sequence: CGDRGFYIGKPGAARSGGPRSRGKGIVDQCCVRGCDLQHLELYC | ||||||
Disulfide bond | 89↔94 | |||||
Sequence: CCVRGC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 45-103 | Insulin-like | ||||
Sequence: RARCGRELVDDLEFVCGDRGFYIGKPGAARSGGPRSRGKGIVDQCCVRGCDLQHLELYC | ||||||
Region | 166-188 | Disordered | ||||
Sequence: STQTSSTHLSSTTETPTFISHIR |
Sequence similarities
Belongs to the insulin family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length188
- Mass (Da)21,328
- Last updated2008-04-08 v1
- ChecksumF38EEA8F400D2637
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EU272146 EMBL· GenBank· DDBJ | ABY88869.1 EMBL· GenBank· DDBJ | mRNA | ||
HQ241070 EMBL· GenBank· DDBJ | ADO16598.1 EMBL· GenBank· DDBJ | mRNA |