B0S255 · NADK_FINM2

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

127320406080100120140160180200220240260
TypeIDPosition(s)Description
Active site53Proton acceptor
Binding site53-54NAD+ (UniProtKB | ChEBI)
Binding site58NAD+ (UniProtKB | ChEBI)
Binding site128-129NAD+ (UniProtKB | ChEBI)
Binding site157NAD+ (UniProtKB | ChEBI)
Binding site168-173NAD+ (UniProtKB | ChEBI)
Binding site192NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      nadK
    • Ordered locus names
      FMG_1027

Organism names

Accessions

  • Primary accession
    B0S255

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10002054171-273NAD kinase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    273
  • Mass (Da)
    30,856
  • Last updated
    2008-04-08 v1
  • Checksum
    469FEEC9B9D5247F
MNNNSKIINIYVNDNQKSLETALIVKDKLEQKGFKPTFDFDENALINLCIGGDGAFLRAVHKYEFSTIPFVGINTGHLGFYQEILIPNIDKFISDLINENYGIEKISLLESKTAIRNSSKTYTHKALNEFVVKSDDSSIVYLDVYIDDNHLESFAGDGIIVSTPSGSTAYNFSAGGSVLYHGLDGFQVTPLAPINSKAYRSLLNSLVVPSKSNVTLYFRDHNFDRKSSIVLADGLNRSYDNVDYVNFTYSDQYINKLVFLKDWYWLNIKDKFL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP008971
EMBL· GenBank· DDBJ
BAG08445.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp