B0S255 · NADK_FINM2
- ProteinNAD kinase
- GenenadK
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids273 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Catalytic activity
- NAD+ + ATP = ADP + NADP+ + H+
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 53 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 53-54 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: DG | ||||||
Binding site | 58 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 128-129 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: NE | ||||||
Binding site | 157 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 168-173 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: TAYNFS | ||||||
Binding site | 192 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: A |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | NAD binding | |
Molecular Function | NAD+ kinase activity | |
Biological Process | NAD metabolic process | |
Biological Process | NADP biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD kinase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Tissierellia > Tissierellales > Peptoniphilaceae > Finegoldia
Accessions
- Primary accessionB0S255
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000205417 | 1-273 | NAD kinase | |||
Sequence: MNNNSKIINIYVNDNQKSLETALIVKDKLEQKGFKPTFDFDENALINLCIGGDGAFLRAVHKYEFSTIPFVGINTGHLGFYQEILIPNIDKFISDLINENYGIEKISLLESKTAIRNSSKTYTHKALNEFVVKSDDSSIVYLDVYIDDNHLESFAGDGIIVSTPSGSTAYNFSAGGSVLYHGLDGFQVTPLAPINSKAYRSLLNSLVVPSKSNVTLYFRDHNFDRKSSIVLADGLNRSYDNVDYVNFTYSDQYINKLVFLKDWYWLNIKDKFL |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length273
- Mass (Da)30,856
- Last updated2008-04-08 v1
- Checksum469FEEC9B9D5247F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP008971 EMBL· GenBank· DDBJ | BAG08445.1 EMBL· GenBank· DDBJ | Genomic DNA |