B0G140 · ATG17_DICDI
- ProteinProbable autophagy-related protein 17
- Geneatg17
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids488 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | Atg1/ULK1 kinase complex | |
Cellular Component | nucleus | |
Cellular Component | phagophore assembly site | |
Cellular Component | phagophore assembly site membrane | |
Molecular Function | molecular adaptor activity | |
Molecular Function | protein kinase activator activity | |
Biological Process | autophagosome assembly | |
Biological Process | autophagy of mitochondrion | |
Biological Process | piecemeal microautophagy of the nucleus |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameProbable autophagy-related protein 17
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Amoebozoa > Evosea > Eumycetozoa > Dictyostelia > Dictyosteliales > Dictyosteliaceae > Dictyostelium
Accessions
- Primary accessionB0G140
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Preautophagosomal structure membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000367254 | 1-488 | Probable autophagy-related protein 17 | ||
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 103-150 | Disordered | |||
Region | 257-284 | Disordered | |||
Compositional bias | 264-284 | Polar residues | |||
Sequence similarities
Belongs to the ATG17 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length488
- Mass (Da)57,014
- Last updated2008-03-18 v1
- Checksum7C6211B043B1BEB2
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 264-284 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAFI02000046 EMBL· GenBank· DDBJ | EDR41068.1 EMBL· GenBank· DDBJ | Genomic DNA |