B0EVF7 · B0EVF7_CANLF
- ProteinP-type Cu(+) transporter
- GeneATP7B
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1447 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | trans-Golgi network | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | copper ion binding | |
Molecular Function | P-type monovalent copper transporter activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameP-type Cu(+) transporter
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Canis
Accessions
- Primary accessionB0EVF7
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 636-655 | Helical | ||||
Sequence: FLCSLVFGIPVMGLMIYMLV | ||||||
Transmembrane | 675-697 | Helical | ||||
Sequence: SILNLIFFILCTFVQLLGGWYFY | ||||||
Transmembrane | 709-735 | Helical | ||||
Sequence: ANMDVLIVLATSIAYTYSLVILVVAVA | ||||||
Transmembrane | 741-762 | Helical | ||||
Sequence: SPVTFFDTPPMLFVFIALGRWL | ||||||
Transmembrane | 905-932 | Helical | ||||
Sequence: YFVPFIIIISTLTLVVWIIIGFIDFGVV | ||||||
Transmembrane | 952-972 | Helical | ||||
Sequence: FAFQTSITVLCIACPCSLGLA | ||||||
Transmembrane | 1307-1329 | Helical | ||||
Sequence: LVLALIYNLVGIPIAAGVFMPIG | ||||||
Transmembrane | 1335-1355 | Helical | ||||
Sequence: WMGSAAMAASSVSVVLSSLQL |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 40-106 | HMA | ||||
Sequence: ATSTISILGMTCQSCVRSIEGRISSLKGIVSIKISLEQGNATVKYMPSILSLPQVCRHIEDMGFEAS | ||||||
Domain | 125-191 | HMA | ||||
Sequence: AVVRLRVEGMTCQSCVSSIEGKLGKLQGVARVRVSLSTQEAVITYQPYLIQPQDLRDHVNDMGFEAV | ||||||
Domain | 239-305 | HMA | ||||
Sequence: VTLQLRVDGMHCQSCVLNIEENIGQLPGVQNVQVSLENRTAQVQYDPSCVTAGALQRAIEALPPGNF | ||||||
Domain | 341-407 | HMA | ||||
Sequence: DTVMLAIVGMTCASCVQSIEGLISQREGVQQISVSLAEGTAVVLYDPSIIGPEELRAAVEEMGFETS | ||||||
Region | 439-465 | Disordered | ||||
Sequence: QEGAPHTEGLPGNHSPGRPSRSPPAST | ||||||
Domain | 470-536 | HMA | ||||
Sequence: QKCFLQITGMTCASCVSNIERKLQKEAGVVSVLVALMAGKAEVKYHPDVIQPLEIAQLIQDLGFEAT | ||||||
Domain | 546-612 | HMA | ||||
Sequence: GDLELIITGMTCASCVHNIESKLTRMAGITYASVALATSKAHVKFDPEIIGPRDIVKVIEEIGFHAS | ||||||
Region | 1097-1121 | Disordered | ||||
Sequence: PGERQRSKQAAPPGTVGGVPEETDE |
Sequence similarities
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length1,447
- Mass (Da)154,638
- Last updated2008-02-26 v1
- Checksum37282052CB97D716
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: I |