B0CVR2 · B0CVR2_LACBS

Function

Catalytic activity

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.
    EC:2.3.2.26 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; protein ubiquitination.

Features

Showing features for active site.

1797100200300400500600700
TypeIDPosition(s)Description
Active site765Glycyl thioester intermediate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionubiquitin protein ligase activity
Biological Processprotein polyubiquitination
Biological Processubiquitin-dependent protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    E3 ubiquitin-protein ligase
  • EC number

Gene names

    • ORF names
      LACBIDRAFT_309180

Organism names

Accessions

  • Primary accession
    B0CVR2

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain1-113C2
Region135-319Disordered
Domain241-274WW
Compositional bias257-274Polar residues
Compositional bias276-291Pro residues
Domain323-356WW
Domain375-408WW
Domain464-797HECT

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    797
  • Mass (Da)
    90,050
  • Last updated
    2008-02-26 v1
  • Checksum
    E82542EEF2B3A972
MASSSRLNDPERSIRVKLYSANGLAKRELLSLPDPFAVLTVDGEQTSTTAIAKKSLAPVWNEHFDVTVRQSSMIAIQIFDHRKFRKRDQGFLGVINIPAAEALSYAASQQGPITRDLTMSSNNLPVYGKISFSFSSPPQSQPSLVHPDRVSYQPPPQDHIHQGQPPMVNHSIRVPNSNPQAHADEDHRPIQPVHPTPSLRPSPSHAALNQPSGMPNRPDPPRPVSSSGAVANRLTDDDAGNPLPPGWERRTDAQNRTYYVDHNNRSTSWHRPLASGQPPTRPPPQAAPPSQTPVRVPSAVAATPTAASVAATPTSPPGSYADVPLPLGWEERRTPQGRPYFVDHHTRTTTWTDPRVTNQQAAVAVPRPAANHNLGPLPSGWEMRLTSTGRVYFVDHNTRTTSWDDPRLPTNVDDNAPQYKRDYRRKVVYFRSQPKMRILPGKCEVKVRRSRVLEDSYASVMGFTGEDLKRRLMVNFDGEDGLDYGGVSREWFFLLSHEIFNPSYGLFEYSTHDNYTLQINPASGINPDHLSYFKFIGRCLGLAIFHRRFLDAYFVPSFYKMILGKHMALADLESVDSDLHRSLVWMLENDITDVLDETFTTAEERFGELVTIELKPGGEEVPVTEENKKEYVDSVVAYRISKRVKEQFDAFMEGLLELVPRDLINVFDERELELLIGGMSEIDMDDWTKFTDYRGYEKTDQVIEWFWQCIRSWPAERKSRLLQFTTGTSRVPVNGFKDLQGSDGPRRFTIEKSGDPMGLPRSHTCFNRLDLPPYQDYESLETKLLFAIEETEGFGQE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias257-274Polar residues
Compositional bias276-291Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DS547093
EMBL· GenBank· DDBJ
EDR13792.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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