B0C4I0 · NDK_ACAM1

Function

function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site9ATP (UniProtKB | ChEBI)
Binding site57ATP (UniProtKB | ChEBI)
Binding site85ATP (UniProtKB | ChEBI)
Binding site91ATP (UniProtKB | ChEBI)
Binding site102ATP (UniProtKB | ChEBI)
Binding site112ATP (UniProtKB | ChEBI)
Active site115Pros-phosphohistidine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionnucleoside diphosphate kinase activity
Biological ProcessCTP biosynthetic process
Biological ProcessGTP biosynthetic process
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoside diphosphate kinase
  • EC number
  • Short names
    NDK
    ; NDP kinase
  • Alternative names
    • Nucleoside-2-P kinase

Gene names

    • Name
      ndk
    • Ordered locus names
      AM1_3733

Organism names

Accessions

  • Primary accession
    B0C4I0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000809521-149Nucleoside diphosphate kinase

Keywords

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the NDK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    149
  • Mass (Da)
    16,379
  • Last updated
    2008-02-26 v1
  • Checksum
    90C5936A6B69A74C
MERTFLAVKPDGVQRGLVGEIISRYEAKGFTLVGLKLMVVSRELAEQHYGEHKEKPFFSGLVDFITSGPVVAMVWEGKGVVAAARKIIGATNPLGSEPGTIRGDFGIDIGRNIIHGSDAVETAQREISLWFKSEELADWSPTLTSWIYE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000828
EMBL· GenBank· DDBJ
ABW28723.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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