the HuD protein is abnormally expressed in the nerve plexuses of the intestinal wall of the terminal rectum of ARM embryonic rats which suggests that HuD may participate in the development and maturation of the ENS in ARM embryonic rats.
Both ZBP1 and HuD bind the zipcode element in rat beta-actin mRNA's 3' UTR. Differences between HuD and ZBP1 were observed in their binding preference to the element.
mTORC1 activity regulation of mRNA stability and high affinity HuD-target mRNA degradation mediates the bidirectional expression of dendritic Kv1.1 ion channels.
Melatonin directly influences intracellular biosynthesis and extracellular secretion of insulin under endoplasmic reticulum (ER)stress via HuD expression in rat insulinoma INS-1E cells.
PKC may play an important role in neuronal differentiation and synaptogenesis via stimulating HuD-mediated mRNA stability and inhibiting CARM1 in hippocampal neurons
findings indicated a specific developmental pattern of expression of HuD in the postnatal cerebellum; data suggest HuD might be involved in the transition of neural progenitors into early neuroblasts
HuD stabilizes the GAP-43 mRNA through a mechanism that is dependent on the length of the poly(A) tail and involves changes in its affinity for the mRNA (Hu antigen D; HuD)
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