A9WR65 · RISB_RENSM

Function

function

Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

Catalytic activity

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.

Features

Showing features for binding site, active site.

115920406080100120140
Type
IDPosition(s)Description
Binding site265-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site58-605-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site80-825-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site85-86(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)
Active site88Proton donor
Binding site1135-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site127(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentriboflavin synthase complex
Molecular Function6,7-dimethyl-8-ribityllumazine synthase activity
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6,7-dimethyl-8-ribityllumazine synthase
  • EC number
  • Short names
    DMRL synthase
    ; LS
    ; Lumazine synthase

Gene names

    • Name
      ribH
    • Ordered locus names
      RSal33209_2344

Organism names

Accessions

  • Primary accession
    A9WR65

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000772451-1596,7-dimethyl-8-ribityllumazine synthase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the DMRL synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    159
  • Mass (Da)
    16,339
  • Last updated
    2008-02-05 v1
  • Checksum
    B9AE0B824EAFEDD3
MSGAGAPVSPQLNAKGLELVIIAASWHEKVMNGLLDGALRAARDAGIEEPRIVRVPGSFELPVAAARLAPDYDAVVALGVVIRGGTPHFEYVCQAATSGLTEVSVRTGVPVGFGLLTCDNDQQALDRAGLPAAPGFAGSKEDKGYEATSAALETALTLR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000910
EMBL· GenBank· DDBJ
ABY24074.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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