A9V5H0 · A9V5H0_MONBE
- ProteinPutative rRNA methyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1021 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
Catalytic activity
- a ribonucleotide in rRNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in rRNA + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 144 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 146 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 164 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 180 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 205 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Active site | 245 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleolus | |
Cellular Component | preribosome, large subunit precursor | |
Molecular Function | rRNA (guanine) methyltransferase activity | |
Molecular Function | rRNA (uridine-2'-O-)-methyltransferase activity | |
Biological Process | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | |
Biological Process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | |
Biological Process | rRNA methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative rRNA methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Choanoflagellata > Craspedida > Salpingoecidae > Monosiga
Accessions
- Primary accessionA9V5H0
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 12-55 | Disordered | |||
Compositional bias | 16-54 | Basic residues | |||
Domain | 113-288 | Ribosomal RNA methyltransferase FtsJ | |||
Domain | 322-485 | DUF3381 | |||
Region | 416-475 | Disordered | |||
Compositional bias | 425-452 | Acidic residues | |||
Region | 651-692 | Disordered | |||
Region | 710-737 | Disordered | |||
Compositional bias | 715-736 | Acidic residues | |||
Region | 754-776 | Disordered | |||
Region | 797-837 | Disordered | |||
Domain | 828-1010 | Ribosomal RNA methyltransferase SPB1-like C-terminal | |||
Region | 982-1021 | Disordered | |||
Compositional bias | 1007-1021 | Basic residues | |||
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,021
- Mass (Da)114,982
- Last updated2008-02-05 v1
- ChecksumBE7118CDC8B9B5AE
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 16-54 | Basic residues | |||
Compositional bias | 425-452 | Acidic residues | |||
Compositional bias | 715-736 | Acidic residues | |||
Compositional bias | 1007-1021 | Basic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH991560 EMBL· GenBank· DDBJ | EDQ87369.1 EMBL· GenBank· DDBJ | Genomic DNA |