A9V5H0 · A9V5H0_MONBE

Function

function

Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.

Catalytic activity

Features

Showing features for binding site, active site.

110211002003004005006007008009001,000
Type
IDPosition(s)Description
Binding site144S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site146S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site164S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site180S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site205S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site245Proton acceptor

GO annotations

AspectTerm
Cellular Componentnucleolus
Cellular Componentpreribosome, large subunit precursor
Molecular FunctionrRNA (guanine) methyltransferase activity
Molecular FunctionrRNA (uridine-2'-O-)-methyltransferase activity
Biological Processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological ProcessrRNA methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative rRNA methyltransferase
  • EC number
  • Alternative names
    • 2'-O-ribose RNA methyltransferase SPB1 homolog

Gene names

    • ORF names
      MONBRDRAFT_33452

Organism names

Accessions

  • Primary accession
    A9V5H0

Proteomes

Subcellular Location

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region12-55Disordered
Compositional bias16-54Basic residues
Domain113-288Ribosomal RNA methyltransferase FtsJ
Domain322-485DUF3381
Region416-475Disordered
Compositional bias425-452Acidic residues
Region651-692Disordered
Region710-737Disordered
Compositional bias715-736Acidic residues
Region754-776Disordered
Region797-837Disordered
Domain828-1010Ribosomal RNA methyltransferase SPB1-like C-terminal
Region982-1021Disordered
Compositional bias1007-1021Basic residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,021
  • Mass (Da)
    114,982
  • Last updated
    2008-02-05 v1
  • Checksum
    BE7118CDC8B9B5AE
MVSCQTFFNTNTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTHTTRGALSLSLSLSLSLSHSFSLSLISFSLGHLRMGKKVKTGKDRRDKFYHLAKETGLRARSAFKLVQLNRKFNFLQQSKVCIDLCAAPGGWMQVAAQNMPPSSLIIGVDLVPIKPIKGCIGLVADITTERCRQMLRKEMKHLKADVVLHDGAPNVGTSWIQDAFTQASLVLKSLKLATEFLVEKGTFVTKVFRSRDYHALMWVFKQLFRKVQATKPTSSRNVSAEIFVVCQGFLAPDRIDPKMLDPKYVFEEIDDGQTLPDIFKDPKRKPRAEGYDDNVKQSMFTSITAEDFVKSDNHLDLLAMHNQIVFDDDSLIAKHPATTGEVRSLAVDLKVLGKKDFRTLIKWRQQMAMMLEEAAKLQRAAEGADGEGSEDEEEDEEGEGSEEDGESADSQDELETALAEAKAEEKAKLKRKRRLKAKEHRKLRERMALQMETPMDMAEDTNERILFNLKAVKNADQLAALDEGDMEAAMDPLMEVADEARPRRHITLDLSEEGSHAMMEEALERDYEQYLERKNKKKRVVRHHNKSSVIEARVDGQDADGDDADFAAAAPASVAADDEDEALENDTGLLVRSASKQRNTAAMWFAQNQFEDLDEDLDLDDEEEERAAALRKGATSSTNGGPASKRRKTAEELAKEYANEEWAEAMGLQFHADDLDESDGELDSADEFDDEDEDDMEGLNTASRRAAAVARARAQAEAAAEAGEDGDEATEQNADFDAAFAQLDQALGNDTKQLAVQAAVGDQVPTKKGDKGRNQGGGFEEVPMDTPESSTNRPGLDAAGLAMATEMIVRRKRREMIEAAYNRFAHNDDPLPMWFADEENPHRERIIPTSREMADEIKQRQREINARPLRRVLEAKARKKQRVGRALDKLTKQAEAIAENDSLTEREKGRQIQQLYKQYNRSRNQKRETTYVVAKRSLAAKRAVRPKGLTGRYQQVDQRMKADRRGMRASARRQKKAAKHRH

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias16-54Basic residues
Compositional bias425-452Acidic residues
Compositional bias715-736Acidic residues
Compositional bias1007-1021Basic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH991560
EMBL· GenBank· DDBJ
EDQ87369.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help