A9UZ24 · BCAT_MONBE
- ProteinBranched-chain-amino-acid aminotransferase
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids390 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Catalytic activity
- L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | branched-chain-amino-acid transaminase activity | |
Molecular Function | L-isoleucine transaminase activity | |
Molecular Function | L-leucine transaminase activity | |
Molecular Function | L-leucine:2-oxoglutarate aminotransferase activity | |
Molecular Function | L-valine transaminase activity | |
Biological Process | L-leucine biosynthetic process | |
Biological Process | valine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBranched-chain-amino-acid aminotransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Choanoflagellata > Craspedida > Salpingoecidae > Monosiga
Accessions
- Primary accessionA9UZ24
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000340237 | 1-390 | Branched-chain-amino-acid aminotransferase | |||
Sequence: MAAALRLTPHMRQAYPVVAAPSVARLSTLDASKLTIETTTQPRERVEKTKLVFGHTFSDHMLKCKWDVNEGWAAPTISPYANLSLAPSSIVLHYAIECFEGMKAFRGDDDRIRLFRPNLNMDRLHRSSVRLALPDFDQDELLKCITELVIKDKDWIPAGRGYSLYLRPTHIGTAEYLGVGKSSSSLLFCINSPSGAYYSTGFKPVSLLADPAYVRAWPGGVGNTKGGCNYAPSIYPQSQAQAQGCQQVLWLFGEDHEVTEVGTMNLFMYWKNEQGEDELITPPLDGTILPGVTRQSIVDMARGWNEFKVSERKFNMGQVSRALKEGRVYEMFGAGTAATVCPIGQIKYLGEDLNVPLALGNSGELTNRIWTDIFDIQYGAVEHEWAPVIA | ||||||
Modified residue | 225 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length390
- Mass (Da)43,290
- Last updated2008-02-05 v1
- ChecksumEB28EE7558FF59D4
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH991550 EMBL· GenBank· DDBJ | EDQ89710.1 EMBL· GenBank· DDBJ | Genomic DNA |