A9QPF5 · A9QPF5_METI4

Function

function

Catalyzes the NAD+-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.

Catalytic activity

Features

Showing features for binding site, site.

139850100150200250300350
Type
IDPosition(s)Description
Binding site123substrate
Binding site147substrate
Binding site148NAD+ (UniProtKB | ChEBI)
Binding site202-203NAD+ (UniProtKB | ChEBI)
Binding site222NAD+ (UniProtKB | ChEBI)
Binding site257-261NAD+ (UniProtKB | ChEBI)
Binding site283NAD+ (UniProtKB | ChEBI)
Site285Important for catalytic activity
Binding site309NAD+ (UniProtKB | ChEBI)
Site333Important for catalytic activity
Binding site333-336NAD+ (UniProtKB | ChEBI)
Binding site381NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionformate dehydrogenase (NAD+) activity
Molecular FunctionNAD binding
Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Biological Processformate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Formate dehydrogenase
  • EC number
  • Short names
    FDH
  • Alternative names
    • NAD-dependent formate dehydrogenase

Gene names

    • Name
      hpr
    • Synonyms
      ldhA
    • Ordered locus names
      Minf_1323

Organism names

Accessions

  • Primary accession
    A9QPF5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain64-363D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Domain156-334D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    398
  • Mass (Da)
    43,654
  • Last updated
    2008-02-05 v1
  • Checksum
    C009C441DB0AE7E6
MAKVLCVLYPDPVDGYPKSYIRDSIPKIESYPGGQTVPNPKGIDFVPGELLGSVSGGLGLRKYLESLGHEFIVTSDKDGPNSVFEKELPDADVVISQPFWPAYLTPERIKKAKNLKLAITAGIGSDHVDIQAAIEAGITVAEITYSNSISVAEHVVMMILSLVRNYLPSHEWAVKGGWNIADCAVRAYDLEGMHVGTVAAGRIGLAVLRRLKPFDVHLHYTDTHRLPAEIERELGVTYHPDVYDMVPHCDVITINCPLHPSTEHLFNDRLFEKCKRGTFLVNTARGKICDRDALVRAVQSGKIAAYAGDVWFPQPPPADHPWRTMPYNGMTPHYSGTTLSAQARYAAGTREILECFFEGRPIREEYLIVKGGKLAGTGAHSYTVGSTTKGVEEALKSA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU223871
EMBL· GenBank· DDBJ
ABX56613.1
EMBL· GenBank· DDBJ
Genomic DNA
CP000975
EMBL· GenBank· DDBJ
ACD83377.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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