A9QH40 · A9QH40_CEREN
- ProteinMajor prion protein
- GenePRNP
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids256 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | Golgi apparatus | |
Cellular Component | plasma membrane | |
Cellular Component | side of membrane | |
Molecular Function | metal ion binding | |
Biological Process | protein homooligomerization |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameMajor prion protein
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Cervidae > Cervinae > Cervus
Accessions
- Primary accessionA9QH40
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Lipid-anchor, GPI-anchor
Membrane ; Lipid-anchor, GPI-anchor
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-24 | Helical | ||||
Sequence: IGSWILVLFVAMWSDVGLC | ||||||
Transmembrane | 233-255 | Helical | ||||
Sequence: ASVILFSSPPVILLISFLIFLIV |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 24-110 | Disordered | ||||
Sequence: CKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGTHSQWNKPSKPKT | ||||||
Domain | 116-131 | Prion/Doppel protein beta-ribbon | ||||
Sequence: AGAAAAGAVVGGLGGY | ||||||
Domain | 203-221 | Prion/Doppel protein beta-ribbon | ||||
Sequence: ETDIKMMERVVEQMCITQY |
Sequence similarities
Belongs to the prion family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length256
- Mass (Da)27,915
- Last updated2008-02-05 v1
- ChecksumE54EAD51D772F4E5
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EU082263 EMBL· GenBank· DDBJ | ABW79881.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082264 EMBL· GenBank· DDBJ | ABW79882.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082265 EMBL· GenBank· DDBJ | ABW79883.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082266 EMBL· GenBank· DDBJ | ABW79884.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082267 EMBL· GenBank· DDBJ | ABW79885.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082268 EMBL· GenBank· DDBJ | ABW79886.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082269 EMBL· GenBank· DDBJ | ABW79887.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082281 EMBL· GenBank· DDBJ | ABW79899.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082282 EMBL· GenBank· DDBJ | ABW79900.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082283 EMBL· GenBank· DDBJ | ABW79901.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082284 EMBL· GenBank· DDBJ | ABW79902.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU082285 EMBL· GenBank· DDBJ | ABW79903.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FJ590751 EMBL· GenBank· DDBJ | ACV50398.1 EMBL· GenBank· DDBJ | Genomic DNA |