A9NFG5 · EX7L_ACHLI

Function

function

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.

Catalytic activity

  • Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.
    EC:3.1.11.6 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentexodeoxyribonuclease VII complex
Molecular Functionexodeoxyribonuclease VII activity
Molecular Functionnucleic acid binding
Biological ProcessDNA catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Exodeoxyribonuclease 7 large subunit
  • EC number
  • Alternative names
    • Exodeoxyribonuclease VII large subunit
      (Exonuclease VII large subunit
      )

Gene names

    • Name
      xseA
    • Ordered locus names
      ACL_0476

Organism names

Accessions

  • Primary accession
    A9NFG5

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10002006541-446Exodeoxyribonuclease 7 large subunit

Interaction

Subunit

Heterooligomer composed of large and small subunits.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the XseA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    446
  • Mass (Da)
    50,804
  • Last updated
    2008-02-05 v1
  • Checksum
    F5858B15101AA98F
MNEQKYLSVSALTEYIKVKLENDNHLKRVFLKGEISNFTHHGSGHLYFSLKDEDAAISAMMFKTYASTLSFKPKAGDKVLVEGYISLYKARGTYSISIFSMTLDGIGELFLKYEQNRKMFQELGYFDESLKKPIPKFPKIIAVITSETGAVIQDIKTTISRRYLLAKIELYPILVQGEGSKDDIVKTLARVNRESQADVIILGRGGGSIEDLWSFNEAEVVVAIHQSKIPVITAIGHETDTTLSDYVSDLRAPTPTAAAELATPNMADLIKEIKDKVQLSQYYMNERIKNYTALILNLDERLELASPKSKLELEHKQIDNLTSKLTYFYKSKLTDNLNQVRLLSQRLTSPDEKIERYKERIETLTSRINLLYKKQVDLKTYEYQSSLKQLQGLDPLRIMQRGFSLTTKNQKVITSIEQINTNDELDIQYKDGTAKVKVLSKEGKHI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000896
EMBL· GenBank· DDBJ
ABX81095.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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