A9JQI4 · A9JQI4_THETE

  • Protein
    K(+)-insensitive pyrophosphate-energized proton pump
  • Gene
    hppa
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for site.

1721100200300400500600700
TypeIDPosition(s)Description
Site476Determinant of potassium independence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    K(+)-insensitive pyrophosphate-energized proton pump
  • EC number
  • Alternative names
    • Membrane-bound proton-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (H(+)-PPase
      )

Gene names

    • Name
      hppa
    • Synonyms
      hppA

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Kra1
  • Taxonomic lineage
    Archaea > Thermoproteota > Thermoprotei > Thermoproteales > Thermoproteaceae > Thermoproteus

Accessions

  • Primary accession
    A9JQI4

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-27Helical
Transmembrane58-76Helical
Transmembrane82-104Helical
Transmembrane131-155Helical
Transmembrane161-179Helical
Transmembrane234-251Helical
Transmembrane257-279Helical
Transmembrane291-314Helical
Transmembrane320-340Helical
Transmembrane361-394Helical
Transmembrane414-436Helical
Transmembrane482-507Helical
Transmembrane527-546Helical
Transmembrane599-631Helical
Transmembrane696-719Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    721
  • Mass (Da)
    75,362
  • Last updated
    2008-02-05 v1
  • Checksum
    5E59E6CD57F2D82E
MAIIPILGLIIGLLGLLYAVYLARWVLSQDPGNEKMRFISNAIATGARAYLFRQYRTLAALLVVLAVAILAAIDIPRGLPGLTALGFVVGALGSMLAGYLGMYVTTRSASRVAQAAASGGMGKALQVSWRAGAVMGLSLASIALMLISGFYLIFSRITAEWAVPLVALGFGASLVTLFMRVGGGIYTKAADLGADLVGKIEAGIPEDDPRNPGVIADNVGDNVGDVAGMAADVYESYIVTVTASIFLAYILGLPSTYIKGIILFASLALLATFVGINSLRTKGVKNPMGSISTAVYVTIAVSIILFFVGALALGLPFVQAIAMASAVSLGAIIAPLVVKITDYYTSYSYSPVRRIAEQAKISPATVIITGYGVGLMSAVPVLLVIIGVLGISYIIGFYAFSSSITAGFASYGPYLAGIFGTALASVGLLIIAGIIITADSYGPVSDNANGVVEMAGLPDNVREVTDVLDSIGNTTKATTKGYAIASAALAALVLFIALMFEIMRSLSTLLHQPFTSLLGTSISEISIINPNVLIGAFIGVIIVYFFTSRTLGAVGRTAMEIVEEIRRQFKEKPGILEWKETPDYARVVDIATRRALGEFLLPGIVVIVVPLVTAFVLGWQALAGLIMGAVISGVPRALLMANAGGAWDNAKKYIELQGLKKTELHKAVVIGDTVGDPFKDTSGPSLNPLIKVLNTLSVVFAFAIILANTHMGIALSGLLHF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AM920405
EMBL· GenBank· DDBJ
CAP46805.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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