A9JQI4 · A9JQI4_THETE
- ProteinK(+)-insensitive pyrophosphate-energized proton pump
- Genehppa
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids721 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
Catalytic activity
- diphosphate + H+(in) + H2O = 2 H+(out) + 2 phosphate
Cofactor
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 476 | Determinant of potassium independence | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameK(+)-insensitive pyrophosphate-energized proton pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Thermoproteales > Thermoproteaceae > Thermoproteus
Accessions
- Primary accessionA9JQI4
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-27 | Helical | ||||
Sequence: ILGLIIGLLGLLYAVYLARWVL | ||||||
Transmembrane | 58-76 | Helical | ||||
Sequence: LAALLVVLAVAILAAIDIP | ||||||
Transmembrane | 82-104 | Helical | ||||
Sequence: LTALGFVVGALGSMLAGYLGMYV | ||||||
Transmembrane | 131-155 | Helical | ||||
Sequence: AGAVMGLSLASIALMLISGFYLIFS | ||||||
Transmembrane | 161-179 | Helical | ||||
Sequence: WAVPLVALGFGASLVTLFM | ||||||
Transmembrane | 234-251 | Helical | ||||
Sequence: YESYIVTVTASIFLAYIL | ||||||
Transmembrane | 257-279 | Helical | ||||
Sequence: YIKGIILFASLALLATFVGINSL | ||||||
Transmembrane | 291-314 | Helical | ||||
Sequence: ISTAVYVTIAVSIILFFVGALALG | ||||||
Transmembrane | 320-340 | Helical | ||||
Sequence: AIAMASAVSLGAIIAPLVVKI | ||||||
Transmembrane | 361-394 | Helical | ||||
Sequence: ISPATVIITGYGVGLMSAVPVLLVIIGVLGISYI | ||||||
Transmembrane | 414-436 | Helical | ||||
Sequence: YLAGIFGTALASVGLLIIAGIII | ||||||
Transmembrane | 482-507 | Helical | ||||
Sequence: YAIASAALAALVLFIALMFEIMRSLS | ||||||
Transmembrane | 527-546 | Helical | ||||
Sequence: IINPNVLIGAFIGVIIVYFF | ||||||
Transmembrane | 599-631 | Helical | ||||
Sequence: FLLPGIVVIVVPLVTAFVLGWQALAGLIMGAVI | ||||||
Transmembrane | 696-719 | Helical | ||||
Sequence: LSVVFAFAIILANTHMGIALSGLL |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length721
- Mass (Da)75,362
- Last updated2008-02-05 v1
- Checksum5E59E6CD57F2D82E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AM920405 EMBL· GenBank· DDBJ | CAP46805.1 EMBL· GenBank· DDBJ | Genomic DNA |