A9G6T8 · F16PA_SORC5
- ProteinFructose-1,6-bisphosphatase class 1
- Genefbp
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids347 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate
Cofactor
Note: Binds 2 magnesium ions per subunit.
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 107 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 128 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 128 | Mg2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 130 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 131 | Mg2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 131-134 | substrate | ||||
Sequence: DGSS | ||||||
Binding site | 224 | substrate | ||||
Sequence: N | ||||||
Binding site | 257 | substrate | ||||
Sequence: Y | ||||||
Binding site | 286 | substrate | ||||
Sequence: K | ||||||
Binding site | 292 | Mg2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | fructose 1,6-bisphosphate 1-phosphatase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | fructose 1,6-bisphosphate metabolic process | |
Biological Process | fructose 6-phosphate metabolic process | |
Biological Process | fructose metabolic process | |
Biological Process | gluconeogenesis | |
Biological Process | sucrose biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFructose-1,6-bisphosphatase class 1
- EC number
- Short namesFBPase class 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Myxococcota > Polyangia > Polyangiales > Polyangiaceae > Sorangium
Accessions
- Primary accessionA9G6T8
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000364722 | 1-347 | Fructose-1,6-bisphosphatase class 1 | |||
Sequence: MSDQRDLSWKPPDAPSRIGITLETYILEGMLGFPAATGAFTSLLNQLGLVAKLVTSKVRRAGLANVLGYTGQTNVQGEVVQKLDEVANETLLSVLGRRGHCAAVVSEELGEMRLLSTDPRAKYIVVVDPLDGSSNIDVNISIGTIFGVLRKSDAKMGADPSDFLRPGRDLVAAGYVLYGSSTLLVITTGLGGVHGFTYDPTVGEFFLSHENIRIPERGSTYSINEGHSARWPEDVRRWNAWIKEDSKPEGRPYGARYVGSLVADAHRTLLKGGIFAYPADRSGQGKLRLLYEASPFAFIFEAAGGKASTGAERILDRVPRSLHERVPLVLGSPRDVEDFEQFVRGER |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length347
- Mass (Da)37,762
- Last updated2008-02-05 v1
- ChecksumE4E516DF39F625C9
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AM746676 EMBL· GenBank· DDBJ | CAN92737.1 EMBL· GenBank· DDBJ | Genomic DNA |