Sobremesa L-type Amino Acid Transporter Expressed in Glia Is Essential for Proper Timing of Development and Brain Growth.Galagovsky D., Depetris-Chauvin A., Maniere G., Geillon F., Berthelot-Grosjean M., Noirot E., Alves G., Grosjean Y.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceFlyBase: FBgn0086917PubMedEurope PMCCell Rep 24:3156-3166.e4 (2018)Mapped to16
The Drosophila CCR4-NOT complex is required for cholesterol homeostasis and steroid hormone synthesis.Zeng J., Kamiyama T., Niwa R., King-Jones K.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCDev Biol 443:10-18 (2018)Mapped to41
Refining a steroidogenic model: an analysis of RNA-seq datasets from insect prothoracic glands.Moulos P., Alexandratos A., Nellas I., Dedos S.G.View abstractCategoriesFunction, ExpressionSourceFlyBase: FBgn0086917PubMedEurope PMCBMC Genomics 19:537-537 (2018)Mapped to54
Kruppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes.Zhang T., Song W., Li Z., Qian W., Wei L., Yang Y., Wang W., Zhou X., Meng M.[...], Cheng D.View abstractCategoriesFunction, ExpressionSourceFlyBase: FBgn0086917PubMedEurope PMCProc Natl Acad Sci U S A 115:3960-3965 (2018)Mapped to16
A polydnavirus-encoded ANK protein has a negative impact on steroidogenesis and development.Ignesti M., Ferrara R., Romani P., Valzania L., Serafini G., Pennacchio F., Cavaliere V., Gargiulo G.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0086917PubMedEurope PMCInsect Biochem Mol Biol 95:26-32 (2018)Mapped to30
Prothoracicotropic hormone modulates environmental adaptive plasticity through the control of developmental timing.Shimell M., Pan X., Martin F.A., Ghosh A.C., Leopold P., O'Connor M.B., Romero N.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0086917PubMedEurope PMCDevelopment 145:dev159699-dev159699 (2018)Mapped to28
Antagonistic actions of juvenile hormone and 20-hydroxyecdysone within the ring gland determine developmental transitions in <i>Drosophila</i>.Liu S., Li K., Gao Y., Liu X., Chen W., Ge W., Feng Q., Palli S.R., Li S.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceFlyBase: FBgn0086917PubMedEurope PMCProc Natl Acad Sci U S A 115:139-144 (2018)Mapped to47
Cooperative Control of Ecdysone Biosynthesis in <i>Drosophila</i> by Transcription Factors Seance, Ouija Board, and Molting Defective.Uryu O., Ou Q., Komura-Kawa T., Kamiyama T., Iga M., Syrzycka M., Hirota K., Kataoka H., Honda B.M.[...], Niwa R.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0086917PubMedEurope PMCGenetics 208:605-622 (2018)Mapped to22
Glue protein production can be triggered by steroid hormone signaling independent of the developmental program in Drosophila melanogaster.Kaieda Y., Masuda R., Nishida R., Shimell M., O'Connor M.B., Ono H.View abstractCategoriesFunction, ExpressionSourceFlyBase: FBgn0086917PubMedEurope PMCDev Biol 430:166-176 (2017)Mapped to6
Warts Signaling Controls Organ and Body Growth through Regulation of Ecdysone.Moeller M.E., Nagy S., Gerlach S.U., Soegaard K.C., Danielsen E.T., Texada M.J., Rewitz K.F.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCCurr Biol 27:1652-1659.e4 (2017)Mapped to24
Characterization of candidate intermediates in the Black Box of the ecdysone biosynthetic pathway in Drosophila melanogaster: Evaluation of molting activities on ecdysteroid-defective larvae.Saito J., Kimura R., Kaieda Y., Nishida R., Ono H.View abstractCategoriesFunction, Phenotypes & VariantsSourceFlyBase: FBgn0086917PubMedEurope PMCJ Insect Physiol 93-94:94-104 (2016)Mapped to4
The Circadian Clock Is a Key Driver of Steroid Hormone Production in Drosophila.Di Cara F., King-Jones K.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCCurr Biol 26:2469-2477 (2016)Mapped to99+
Ouija board: A transcription factor evolved for only one target in steroid hormone biosynthesis in the fruit fly Drosophila melanogaster.Niwa Y.S., Niwa R.View abstractAnnotationStudy indicates that the expression of spookier in the ecdysteroid biosynthesis pathway requires ouib protein in dorsophila. (review)CategoryFunctionSourceFlyBase: FBgn0086917, GeneRif: 5740359PubMedEurope PMCTranscription 7:196-202 (2016)Mapped to4
The Insect Prothoracic Gland as a Model for Steroid Hormone Biosynthesis and Regulation.Ou Q., Zeng J., Yamanaka N., Brakken-Thal C., O'Connor M.B., King-Jones K.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCCell Rep 16:247-262 (2016)Mapped to99+
Drosophila 4EHP is essential for the larval-pupal transition and required in the prothoracic gland for ecdysone biosynthesis.Valzania L., Ono H., Ignesti M., Cavaliere V., Bernardi F., Gamberi C., Lasko P., Gargiulo G.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCDev Biol 410:14-23 (2016)Mapped to36
Transcriptional regulation of insect steroid hormone biosynthesis and its role in controlling timing of molting and metamorphosis.Niwa Y.S., Niwa R.View abstractCategoriesFunction, ExpressionSourceFlyBase: FBgn0086917PubMedEurope PMCDev Growth Differ 58:94-105 (2016)Mapped to99+
The Drosophila zinc finger transcription factor Ouija Board controls ecdysteroid biosynthesis through specific regulation of spookier.Komura-Kawa T., Hirota K., Shimada-Niwa Y., Yamauchi R., Shimell M., Shinoda T., Fukamizu A., O'Connor M.B., Niwa R.View abstractAnnotationThese observations imply that the main biological function of Ouib is to specifically regulate spookier transcription during Drosophila development.CategoryFunctionSourceFlyBase: FBgn0086917, GeneRif: 5740359PubMedEurope PMCPLoS Genet. 11:E1005712-E1005712 (2015)Cited in1Mapped to23
dTAF10- and dTAF10b-Containing Complexes Are Required for Ecdysone-Driven Larval-Pupal Morphogenesis in Drosophila melanogaster.Pahi Z., Kiss Z., Komonyi O., Borsos B.N., Tora L., Boros I.M., Pankotai T.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCPLoS One 10:e0142226-e0142226 (2015)Mapped to44
CDK8-Cyclin C Mediates Nutritional Regulation of Developmental Transitions through the Ecdysone Receptor in Drosophila.Xie X.J., Hsu F.N., Gao X., Xu W., Ni J.Q., Xing Y., Huang L., Hsiao H.C., Zheng H.[...], Ji J.Y.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCPLoS Biol 13:e1002207-e1002207 (2015)Mapped to99+
The insulator protein CTCF regulates Drosophila steroidogenesis.Fresan U., Cuartero S., O'Connor M.B., Espinas M.L.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCBiol Open 4:852-857 (2015)Mapped to5
Acetylations of Ftz-F1 and histone H4K5 are required for the fine-tuning of ecdysone biosynthesis during Drosophila metamorphosis.Borsos B.N., Pankotai T., Kovacs D., Popescu C., Pahi Z., Boros I.M.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCDev Biol 404:80-87 (2015)Mapped to14
Production of systemically circulating Hedgehog by the intestine couples nutrition to growth and development.Rodenfels J., Lavrynenko O., Ayciriex S., Sampaio J.L., Carvalho M., Shevchenko A., Eaton S.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCGenes Dev 28:2636-2651 (2014)Mapped to8
Unexpected role of the steroid-deficiency protein ecdysoneless in pre-mRNA splicing.Claudius A.K., Romani P., Lamkemeyer T., Jindra M., Uhlirova M.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCPLoS Genet. 10:E1004287-E1004287 (2014)Cited in1Mapped to23
INO80-dependent regression of ecdysone-induced transcriptional responses regulates developmental timing in Drosophila.Neuman S.D., Ihry R.J., Gruetzmacher K.M., Bashirullah A.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCDev Biol 387:229-239 (2014)Mapped to28
Dynamic feedback circuits function as a switch for shaping a maturation- inducing steroid pulse in Drosophila.Moeller M.E., Danielsen E.T., Herder R., O'Connor M.B., Rewitz K.F.View abstractCategoryFunctionSourceFlyBase: FBgn0086917PubMedEurope PMCDevelopment 140:4730-4739 (2013)Mapped to31