A8WZ54 · A8WZ54_CAEBR

  • Protein
    ATP-dependent DNA helicase PIF1
  • Gene
    pif-1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, dna binding.

168350100150200250300350400450500550600650
Type
IDPosition(s)Description
Binding site271-278ATP (UniProtKB | ChEBI)
DNA binding618-637

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentnucleus
Cellular Componentreplication fork
Molecular Function5'-3' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Biological ProcessDNA duplex unwinding
Biological ProcessDNA recombination
Biological ProcessDNA repair
Biological ProcessDNA replication
Biological Processmitochondrial genome maintenance
Biological Processtelomere maintenance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase PIF1
  • EC number
  • Alternative names
    • DNA repair and recombination helicase PIF1

Gene names

    • Name
      pif-1
    • Synonyms
      Cbr-pif-1
      , PIF1
    • ORF names
      CBG05155
      , CBG_05155

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • AF16
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    A8WZ54

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region170-206Disordered
Compositional bias174-206Polar residues
Domain503-545DNA helicase Pif1-like 2B

Sequence similarities

Belongs to the helicase family. PIF1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    683
  • Mass (Da)
    76,121
  • Last updated
    2008-01-15 v1
  • Checksum
    DD33315F912AB12C
MNKNLENAENDGISESPSNCTYCYTLTCSLRIESTSSSKKKTPINAKNAILTVGRNSNRKIHLQIELKTSQTGQPAVVSYDATDAVVHLQNVANGKCTVEIPSMSIMLQMFNCAPRKLNVFMKSLQAKLDIMKAEKQPISAVSKNFSRPPAVFNVLSPLTVGEMRKVKKLREPSSLASSASTSSNGSKTATTPKRRNSTNQNLENRILNRSISLKRMTSFARCDKEQSEALTSLKPLKDAPSITERIQLTNEQKSVVRCVINSRVSVFFTGSAGTGKSVILRRIIEMLPAGSTYITAATGVAASQIGGITLHAFCGFRYENATAEQCLQQVLRHTHMVKQWKQCAHLIIDEISMIDSEFFEILEYVARAVRNNDEPFGGIQLIITGDFFQLPPVTKDNKEPVFCFESEAWSRCVQLTIVLKNVKRQNDMEFVEILNSVRIGKCDQLSADRLQASSQNEFPAHVIPTKLCTHSEDAERINQTSLQNSEGVQKTFHAYDDSEFNDAKCRTMAVKTLILKEGSQVMLIKNLDVFKGLCNGSRGFVEKFGENGNPIVRFVAQNVAIEIRRSKFSIRVPGSDVPYIRRQYPLQLAWAISIHKSQGMTLDCAEISLERVFADGQAYVALSRARSLAAIRITGFDVSCVRANSKVIDFYKSIENDYHLNDDDGDDDRLSISSKIKRFRSI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias174-206Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HE600988
EMBL· GenBank· DDBJ
CAP25664.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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