A8WZ54 · A8WZ54_CAEBR
- ProteinATP-dependent DNA helicase PIF1
- Genepif-1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids683 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Cofactor
Features
Showing features for binding site, dna binding.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 271-278 | ATP (UniProtKB | ChEBI) | |||
DNA binding | 618-637 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Cellular Component | replication fork | |
Molecular Function | 5'-3' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Biological Process | DNA duplex unwinding | |
Biological Process | DNA recombination | |
Biological Process | DNA repair | |
Biological Process | DNA replication | |
Biological Process | mitochondrial genome maintenance | |
Biological Process | telomere maintenance |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent DNA helicase PIF1
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis
Accessions
- Primary accessionA8WZ54
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 170-206 | Disordered | |||
Compositional bias | 174-206 | Polar residues | |||
Domain | 503-545 | DNA helicase Pif1-like 2B | |||
Sequence similarities
Belongs to the helicase family. PIF1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length683
- Mass (Da)76,121
- Last updated2008-01-15 v1
- ChecksumDD33315F912AB12C
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 174-206 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
HE600988 EMBL· GenBank· DDBJ | CAP25664.1 EMBL· GenBank· DDBJ | Genomic DNA |