A8NIX8 · A8NIX8_COPC7
- Proteinpyranose dehydrogenase (acceptor)
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids608 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the single-oxidation or sequential double oxidation reaction of carbohydrates primarily at carbon-2 and/or carbon-3 with the concomitant reduction of the flavin. The enzyme exhibits a broad sugar substrate specificity, oxidizing different aldopyranoses to the corresponding C-1, C-2, C-3 or C-1,2, C-2,3 and C-3,4 (di)dehydro sugars with substrate-specific regioselectivity. Accepts only a narrow range of electron acceptors such as substituted benzoquinones and complexed metal ions and reacts extremely slowly with O2 as acceptor. May play a role in the natural recycling of plant matter by oxidizing all major monosaccharides in lignocellulose and by reducing quinone compounds or reactive radical species generated during lignin depolymerization.
Catalytic activity
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 244 | FAD (UniProtKB | ChEBI) | |||
Active site | 544 | Proton donor | |||
Active site | 587 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | oxidoreductase activity, acting on CH-OH group of donors |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namepyranose dehydrogenase (acceptor)
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Psathyrellaceae > Coprinopsis
Accessions
- Primary accessionA8NIX8
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 93-116 | Glucose-methanol-choline oxidoreductase N-terminal | |||
Domain | 286-300 | Glucose-methanol-choline oxidoreductase N-terminal | |||
Sequence similarities
Belongs to the GMC oxidoreductase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length608
- Mass (Da)67,449
- Last updated2008-01-15 v1
- Checksum87B4EB93654D3D6E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AACS02000010 EMBL· GenBank· DDBJ | EAU87691.1 EMBL· GenBank· DDBJ | Genomic DNA |