A8NIX8 · A8NIX8_COPC7

Function

function

Catalyzes the single-oxidation or sequential double oxidation reaction of carbohydrates primarily at carbon-2 and/or carbon-3 with the concomitant reduction of the flavin. The enzyme exhibits a broad sugar substrate specificity, oxidizing different aldopyranoses to the corresponding C-1, C-2, C-3 or C-1,2, C-2,3 and C-3,4 (di)dehydro sugars with substrate-specific regioselectivity. Accepts only a narrow range of electron acceptors such as substituted benzoquinones and complexed metal ions and reacts extremely slowly with O2 as acceptor. May play a role in the natural recycling of plant matter by oxidizing all major monosaccharides in lignocellulose and by reducing quinone compounds or reactive radical species generated during lignin depolymerization.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • a pyranoside + acceptor = a pyranosid-3,4-diulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)
  • a pyranoside + acceptor = a pyranosid-3-ulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)
  • pyranose + acceptor = pyranos-2,3-diulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)
  • pyranose + acceptor = pyranos-2-ulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)
  • pyranose + acceptor = pyranos-3-ulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site244FAD (UniProtKB | ChEBI)
Active site544Proton donor
Active site587Proton acceptor

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionoxidoreductase activity, acting on CH-OH group of donors

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    pyranose dehydrogenase (acceptor)
  • EC number

Gene names

    • ORF names
      CC1G_08727

Organism names

Accessions

  • Primary accession
    A8NIX8

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain93-116Glucose-methanol-choline oxidoreductase N-terminal
Domain286-300Glucose-methanol-choline oxidoreductase N-terminal

Sequence similarities

Belongs to the GMC oxidoreductase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    608
  • Mass (Da)
    67,449
  • Last updated
    2008-01-15 v1
  • Checksum
    87B4EB93654D3D6E
MPLIANPEEIANKTFDYVVVGAGTAGLTLATRLTEDENVSVLVLEAGIRHHGDPNIDVPAQYGATFMQPKYDWAFKTVKQKHSNDNEHVWARGKGLGGSSNMNFFCWIKPPAEDVDAIEKLGNPGWNWADYEAYSKKSETFHPAVPEIAEKYPHTYNAKFRGTSGPIQVTVPLHAHTLDEIWQNTLANKGVRKIEDPYGGDITGTWIAANNVDPKTWKRSYSATAYWEPNQHRPNLHVITEAYVTRIVWADEKDSEGNLVATGVQFVHGSTERTVLASKEVVLSAGTVKTPQILELSGVGKPEILSKFGIDTKLNLPGVGENVQEHHFMWVIYELDTTKGDHQTLDMFFEPGYVQESLKLHAEGKGLHRTGITSFAFLPLSSRDPKAAAALIDELEADLKKKKESGEISPALAKQYDIQLEILRNDKVPDMEFIVFPGYFMCPASQGTGRRFMTVISSLNHPISRGYIHIKSNNPLDDPEIDANYFGHNFDLKVLLEHVKYIRSLEDTEPFKSHTIKEVVPGPECASDADIENHIKNSHITTFHTVGSASMLPREDGGVVDPKLKVYGTKNLRVADLSIVPLHIAAHMQATAYVIGEKAADLIKADAK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AACS02000010
EMBL· GenBank· DDBJ
EAU87691.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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