A8N8Y7 · A8N8Y7_COPC7
- ProteinATP-dependent DNA helicase PIF1
- GenePIF1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids622 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
Catalytic activity
- ATP + H2O = ADP + H+ + phosphate
Cofactor
Features
Showing features for binding site, dna binding.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Molecular Function | 5'-3' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Biological Process | DNA recombination | |
Biological Process | DNA repair | |
Biological Process | mitochondrial genome maintenance | |
Biological Process | telomere maintenance |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent DNA helicase PIF1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Psathyrellaceae > Coprinopsis
Accessions
- Primary accessionA8N8Y7
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-27 | Polar residues | ||||
Sequence: MSSRKAMSGLGSVKRDWSQSSLPASSQ | ||||||
Region | 1-145 | Disordered | ||||
Sequence: MSSRKAMSGLGSVKRDWSQSSLPASSQEVPIPWEPSPPRQQPQKRPMTDAEKRLANIQAALQSVQSNKPPAPLQTSEAANRRPKRPSLEDADAPPSKKRQLPASWAQSNSGFGKDSIAAPQTSGRSSKPPSSKGRVITPSSSGSS | ||||||
Compositional bias | 58-74 | Polar residues | ||||
Sequence: QAALQSVQSNKPPAPLQ | ||||||
Compositional bias | 82-96 | Basic and acidic residues | ||||
Sequence: RPKRPSLEDADAPPS | ||||||
Compositional bias | 101-145 | Polar residues | ||||
Sequence: LPASWAQSNSGFGKDSIAAPQTSGRSSKPPSSKGRVITPSSSGSS | ||||||
Domain | 173-470 | AAA+ ATPase | ||||
Sequence: EGHSVFYTGSAGTGKSVLLREIIKVLNDKYKRGSGAVAITASTGIAACNIGGTTIHSFAGIGLGIEPAEQLATKIRRTNRKAFTRWTRTKVLIIDEISMVEGDLFDKLAKIGSILRGKPEPFGGIQVIVTGDFFQLPPVTKSSSVKFAFEAETWSTTLKHTFNLTKVFRQRDQTFVDMLNEMRFGTLSQKSIAKFYQLARPLHFEDGVESTELFPIRDQVDASNHTRMSRLQTEEEVYRAHDSGTMPMGSSRTKLLASFMVPGEMRLRIGAQVMLVKNYDEILVNGTLGKVVDFVDPD |
Sequence similarities
Belongs to the helicase family. PIF1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length622
- Mass (Da)68,382
- Last updated2010-08-10 v2
- Checksum57FDD160EDA10D4F
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-27 | Polar residues | ||||
Sequence: MSSRKAMSGLGSVKRDWSQSSLPASSQ | ||||||
Compositional bias | 58-74 | Polar residues | ||||
Sequence: QAALQSVQSNKPPAPLQ | ||||||
Compositional bias | 82-96 | Basic and acidic residues | ||||
Sequence: RPKRPSLEDADAPPS | ||||||
Compositional bias | 101-145 | Polar residues | ||||
Sequence: LPASWAQSNSGFGKDSIAAPQTSGRSSKPPSSKGRVITPSSSGSS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AACS02000007 EMBL· GenBank· DDBJ | EAU90478.2 EMBL· GenBank· DDBJ | Genomic DNA |