A8N8Y7 · A8N8Y7_COPC7

Function

function

DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, dna binding.

TypeIDPosition(s)Description
Binding site181-188ATP (UniProtKB | ChEBI)
DNA binding575-594

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentnucleus
Molecular Function5'-3' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Biological ProcessDNA recombination
Biological ProcessDNA repair
Biological Processmitochondrial genome maintenance
Biological Processtelomere maintenance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase PIF1
  • EC number
  • Alternative names
    • DNA repair and recombination helicase PIF1

Gene names

    • Name
      PIF1
    • ORF names
      CC1G_00862

Organism names

Accessions

  • Primary accession
    A8N8Y7

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-27Polar residues
Region1-145Disordered
Compositional bias58-74Polar residues
Compositional bias82-96Basic and acidic residues
Compositional bias101-145Polar residues
Domain173-470AAA+ ATPase

Sequence similarities

Belongs to the helicase family. PIF1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    622
  • Mass (Da)
    68,382
  • Last updated
    2010-08-10 v2
  • Checksum
    57FDD160EDA10D4F
MSSRKAMSGLGSVKRDWSQSSLPASSQEVPIPWEPSPPRQQPQKRPMTDAEKRLANIQAALQSVQSNKPPAPLQTSEAANRRPKRPSLEDADAPPSKKRQLPASWAQSNSGFGKDSIAAPQTSGRSSKPPSSKGRVITPSSSGSSIFNNNSKKGVAAVFLSQEQLHILKLVQEGHSVFYTGSAGTGKSVLLREIIKVLNDKYKRGSGAVAITASTGIAACNIGGTTIHSFAGIGLGIEPAEQLATKIRRTNRKAFTRWTRTKVLIIDEISMVEGDLFDKLAKIGSILRGKPEPFGGIQVIVTGDFFQLPPVTKSSSVKFAFEAETWSTTLKHTFNLTKVFRQRDQTFVDMLNEMRFGTLSQKSIAKFYQLARPLHFEDGVESTELFPIRDQVDASNHTRMSRLQTEEEVYRAHDSGTMPMGSSRTKLLASFMVPGEMRLRIGAQVMLVKNYDEILVNGTLGKVVDFVDPDKLGDELASYTILGGTSTSPTGTLTVKKMLGAKRYPVVDFYTPKITRRRVLVLQDSWKSELPTGEVQLSRVQLPLILAWAMSIHKSQGQTLERVKVDLDKVFEKGQAYVALSRATSLEGLQVINFRPEKVQAHSKVLAWSKTLKTVTDTQNTP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-27Polar residues
Compositional bias58-74Polar residues
Compositional bias82-96Basic and acidic residues
Compositional bias101-145Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AACS02000007
EMBL· GenBank· DDBJ
EAU90478.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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