A8N783 · A8N783_COPC7

Function

function

Catalyzes the NAD+-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, site.

137450100150200250300350
Type
IDPosition(s)Description
Binding site106substrate
Binding site130substrate
Binding site185-186NAD+ (UniProtKB | ChEBI)
Binding site206NAD+ (UniProtKB | ChEBI)
Binding site241-245NAD+ (UniProtKB | ChEBI)
Binding site267NAD+ (UniProtKB | ChEBI)
Site269Important for catalytic activity
Binding site293NAD+ (UniProtKB | ChEBI)
Site322Important for catalytic activity
Binding site322-325NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionformate dehydrogenase (NAD+) activity
Molecular FunctionNAD binding
Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Biological Processformate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Formate dehydrogenase
  • EC number
  • Short names
    FDH
  • Alternative names
    • NAD-dependent formate dehydrogenase

Gene names

    • ORF names
      CC1G_03226

Organism names

Accessions

  • Primary accession
    A8N783

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain55-350D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Domain140-311D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    374
  • Mass (Da)
    40,873
  • Last updated
    2010-08-10 v2
  • Checksum
    EA9171AD734CF2AA
MKVLAILYDGGKAAEEEPRLLGTTENKLGIKDWLESLGHELVAVHPASTQRAIIQVSSSKEGPDSDFQKHIVDAEVLITTPFHPGYLTRELIEKAKNLKLCITAGVGSDHIDLNAAVDHRIQVLEVSGSNVVSVAEHVVMSILLLVRNFVPAHEMIERGDWEVARIARNAFDLEGKVVGTIGAGRIGYRVLQRLLPFDCKELLYYDYAPLPPAAAEAVKTRRVEDLKDFVSQCDVITVNCPLHEGTRGLVNADLLKHFKKGAWLVNTARGAICDKDAVAEALKSGQLSGYAGDVWDVQPAPKDHVWRTAKNPLGGGNGMVPHYSGTTLDAQARYANGAKQILENYLNGKAQDPQNIIVGLGRYETTAYGQRDKK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AACS02000003
EMBL· GenBank· DDBJ
EAU91058.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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